New high resolution mass spectrometry facilities for macromolecules and metabolites at the University of East Anglia

Le Brun, Nick (Principal Investigator)
Butt, Julea (Co-Investigator)
Gates, Andrew (Co-Investigator)
Hutchings, Matt (Co-Investigator)
Le Gall, Gwenaelle (Co-Investigator)
Searcey, Mark (Co-Investigator)
Todd, Jonathan (Co-Investigator)
Waller, Zoe (Co-Investigator)
Wilson, Philip (Researcher)
Goodey, Kimberly (Technician)
Hinchliffe, Antony (Technician)

4 Article

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2024

Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway
Olivieri, P., Klabes, M., Crack, J. C., Lehmann, A., Bennett, S. P., Le Brun, N. E. & Leimkuhler, S., 6 Aug 2024, In: Microbiology Spectrum. 12, 8, e00949-24.
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CyaY and TusA regulate ISC- and SUF-mediated l-cysteine desulfurase activity
Olivieri, P., Crack, J. C., Lehmann, A., Le Brun, N. E. & Leimkuhler, S., 1 Nov 2024, In: RSC Chemical Biology. 5, 11, p. 1165-1176 12 p.
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Light-activated azobenzene peptide inhibitor of the PD-1/PD-L1 interaction
Hayward, D., Goddard, Z. R., Cominetti, M. M. D., Searcey, M. & Beekman, A. M., 14 Aug 2024, In: Chemical Communications. 60, 63, p. 8228-8231 4 p.
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2022

Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron-sulfur cluster assembly
Bennett, S. P., Crack, J. C., Puglisi, R., Pastore, A. & Le Brun, N. E., 21 Dec 2022, In: Chemical Science. 14, 1, p. 78-95 18 p.
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9 Citations (Scopus)

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