The collective bioactivity of dietary flavonoids: importance of specific structural characteristics for cardiovascular benefits

Kay, Colin (Principal Investigator)
Cassidy, Aedin (Co-Investigator)
O'Connell, Maria (Co-Investigator)

Status	Finished
Effective start/end date	28/03/11 → 27/03/14

Funding

Biotechnology and Biological Sciences Research Council: £357,230.32

Cardiovascular mechanisms of action of anthocyanins may be associated with the impact of microbial metabolites on heme oxygenase-1 in vascular smooth muscle cells
Warner, E. F., Rodriguez-Ramiro, I., O'Connell, M. A. & Kay, C. D., 13 Apr 2018, In: Molecules. 23, 4, 898.
Research output: Contribution to journal › Article › peer-review

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17 Citations (Scopus)

33 Downloads (Pure)
Common phenolic metabolites of flavonoids, but not their unmetabolized precursors, reduce the secretion of vascular cellular adhesion molecules by human endothelial cells
Warner, E. F., Zhang, Q., Raheem, K. S., O'Hagan, D., O'Connell, M. A. & Kay, C. D., 1 Mar 2016, In: Journal of Nutrition. 146, 3, p. 465-473 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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78 Citations (Scopus)

29 Downloads (Pure)
Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelialcells
Amin, H. P., Czank, C., Raheem, S., Zhang, Q., Botting, N. P., Cassidy, A. & Kay, C., Jun 2015, In: Molecular Nutrition & Food Research. 59, 6, p. 1095–1106 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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137 Citations (Scopus)

14 Downloads (Pure)