Understanding the molecular mechanism of iron-sulfur cluster biogenesis

Le Brun, Nick (Principal Investigator)

Status	Finished
Effective start/end date	1/01/19 → 31/12/21

Funding

Biotechnology and Biological Sciences Research Council: £370,811.00

4 Article
1 Review article

Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway
Olivieri, P., Klabes, M., Crack, J. C., Lehmann, A., Bennett, S. P., Le Brun, N. E. & Leimkuhler, S., 6 Aug 2024, In: Microbiology Spectrum. 12, 8, e00949-24.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Downloads (Pure)
Iron–sulfur clusters as inhibitors and catalysts of viral replication
Honarmand Ebrahimi, K., Ciofi-Baffoni, S., Hagedoorn, P-L., Nicolet, Y., Le Brun, N. E., Hagen, W. R. & Armstrong, F. A., Mar 2022, In: Nature Chemistry. 14, 3, p. 253–266 14 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
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26 Citations (Scopus)

17 Downloads (Pure)
Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron-sulfur cluster assembly
Bennett, S. P., Crack, J. C., Puglisi, R., Pastore, A. & Le Brun, N. E., 21 Dec 2022, In: Chemical Science. 14, 1, p. 78-95 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

9 Citations (Scopus)

10 Downloads (Pure)