Understanding the molecular mechanism of iron-sulfur cluster biogenesis

Research output

Research output per year 2021 2021 2022 2024 2024

• 5 Article
• 2 Review article

Research output per year

Research output per year

Search results

• 2024

  Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway

  Olivieri, P., Klabes, M., Crack, J. C., Lehmann, A., Bennett, S. P., Le Brun, N. E. & Leimkuhler, S., 6 Aug 2024, In: Microbiology Spectrum. 12, 8, e00949-24.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  6 Downloads (Pure)

• CyaY and TusA regulate ISC- and SUF-mediated l-cysteine desulfurase activity

  Olivieri, P., Crack, J. C., Lehmann, A., Le Brun, N. E. & Leimkuhler, S., 1 Nov 2024, In: RSC Chemical Biology. 5, 11, p. 1165-1176 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)
• 2022

  Iron–sulfur clusters as inhibitors and catalysts of viral replication

  Honarmand Ebrahimi, K., Ciofi-Baffoni, S., Hagedoorn, P-L., Nicolet, Y., Le Brun, N. E., Hagen, W. R. & Armstrong, F. A., Mar 2022, In: Nature Chemistry. 14, 3, p. 253–266 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  32 Citations (Scopus)

  27 Downloads (Pure)

• Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron-sulfur cluster assembly

  Bennett, S. P., Crack, J. C., Puglisi, R., Pastore, A. & Le Brun, N. E., 21 Dec 2022, In: Chemical Science. 14, 1, p. 78-95 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  11 Downloads (Pure)

• The di-iron protein YtfE is a nitric oxide-generating nitrite reductase involved in management of nitrosative stress

  Crack, J. C., Balasiny, B. K., Bennett, S. P., Rolfe, M. D., Froes, A., MacMillan, F., Green, J., Cole, J. A. & Le Brun, N. E., 27 Apr 2022, In: Journal of the American Chemical Society. 144, 16, p. 7129–7145 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  13 Citations (Scopus)

  11 Downloads (Pure)
• 2021

  Biological iron-sulfur clusters: mechanistic insights from mass spectrometry

  Crack, J. & Le Brun, N., 1 Dec 2021, In: Coordination Chemistry Reviews. 448, 214171.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  15 Citations (SciVal)

  10 Downloads (Pure)

• Sensing mechanisms of iron–sulfur cluster regulatory proteins elucidated using native mass spectrometry

  Crack, J. C., Gray, E. & Le Brun, N. E., 21 Jun 2021, In: Dalton Transactions. 50, 23, p. 7887-7897 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  17 Citations (SciVal)

  12 Downloads (Pure)