Urine detection of prostate cancer cells as novel method for cancer diagnosis

Project Details

StatusFinished
Effective start/end date1/01/12 → 31/05/18

Funding

  • Bob Champion Cancer Trust: £229,101.58

  • Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

    Cooper, C. S., Eeles, R. A., Wedge, D. C., Van Loo, P., Gundem, G., Alexandrov, L. B., Kreymer, B., Butler, A., Lynch, A., Edwards, S. E., Camacho, N., Massie, C. E., Kote-Jarai, Z., Dennis, N., Merson, S., Leongamornlert, D. A., Zamora, J., Kay, J., Luxton, H. J., Corbishley, C., & 53 othersThomas, S., Nik-Zainal, S., Ramakrishna, M., O'Meara, S., Matthews, L., Clark, J., Hurst, R., Mithen, R., Bristow, R. G., Boutros, P. C., Fraser, M., Cooke, S., Raine, K., Jones, D., Menzies, A., Stebbings, L., Hinton, J., Teague, J., McLaren, S., Mudie, L., Hardy, C., Anderson, E., Joseph, O., Goody, V., Robinson, B., Maddison, M., Gamble, SJ., Greenman, C., Berney, D., Hazell, S., Livni, N., the ICGC Prostate Group, Fisher, C., Ogden, C., Kumar, P., Thompson, A., Woodhouse, C. J., Nicol, D., Mayer, E., Dudderidge, T., Shah, N., Gnanapragasam, V., Voet, T., Campbell, P., Futreal, P. A., Easton, D. F., Warren, A. Y., Foster, C. S., Stratton, M. R., Whitaker, H. C., McDermott, U., Brewer, D. S. & Neal, D. E., Apr 2015, In: Nature Genetics. 47, p. 367–372 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    356 Citations (Scopus)
    23 Downloads (Pure)

  • Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

    Ross-Adams, H., Lamb, A. D., Dunning, M. J., Halim, S., Lindberg, J., Massie, C. M., Egevad, L. A., Russell, R., Ramos-Montoya, A., Vowler, S. L., Sharma, N. L., Kay, J., Whitaker, H., Clark, J., Hurst, R., Gnanapragasam, V. J., Shah, N. C., Warren, A. Y., Cooper, C. S., Lynch, A. G., & 4 othersStark, R., Mills, I. G., Groenberg, H. & Neal, D. E., Sept 2015, In: EBioMedicine. 2, 9, p. 1133–1144 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    256 Citations (Scopus)
    18 Downloads (Pure)

  • The evolutionary history of lethal metastatic prostate cancer

    Gundem, G., Van Loo, P., Kremeyer, B., Alexandrov, L. B., Tubio, J. M. C., Papaemmanuil, E., Brewer, D., Kallio, H., Högnäs, H., Annala, M., Kivinummi, K., Goody, V., Latimer, C., O'Meara, S., Dawson, K., Isaacs, W., Emmert-Buck, M. R., Nykter, M., Foster, C. S., Kote-Jarai, Z., & 11 othersEaston, D. F., Whitaker, H. C., ICGC Prostate UK Group*, Neal, D. E., Cooper, C. S., Eeles, R. A., Visakorpi, T., Campbell, P., McDermott, U., Wedge, D. C. & Bova, G. S., 16 Apr 2015, In: Nature. 520, 7547, p. 353–357 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    1172 Citations (Scopus)
    39 Downloads (Pure)