α-amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

Sean P. Bew; Laurent Legentil; Vincent Scholier; Sunil V. Sharma

doi:10.1039/b614371g

α-amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

Sean P. Bew, Laurent Legentil, Vincent Scholier, Sunil V. Sharma

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The first synthesis of innovative α-amino acid conjugates of Tröger base is reported; their potential application as conformationally restricted scaffolds is proposed and has been investigated using high level ab initio calculations. © The Royal Society of Chemistry.

Original language	English
Pages (from-to)	389-391
Number of pages	3
Journal	Chemical Communications
Issue number	4
DOIs	https://doi.org/10.1039/b614371g
Publication status	Published - 1 Jan 2007

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10.1039/b614371g

Cite this

@article{b4d78c8d840c4fbd906a05562ea2b516,

title = "α-amino acid Tr{\"o}ger base derivatives, possible conformationally restricted scaffolds?",

abstract = "The first synthesis of innovative α-amino acid conjugates of Tr{\"o}ger base is reported; their potential application as conformationally restricted scaffolds is proposed and has been investigated using high level ab initio calculations. {\textcopyright} The Royal Society of Chemistry.",

author = "Bew, {Sean P.} and Laurent Legentil and Vincent Scholier and Sharma, {Sunil V.}",

year = "2007",

month = jan,

day = "1",

doi = "10.1039/b614371g",

language = "English",

pages = "389--391",

journal = "Chemical Communications",

issn = "1359-7345",