α-amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

Sean P. Bew, Laurent Legentil, Vincent Scholier, Sunil V. Sharma

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The first synthesis of innovative α-amino acid conjugates of Tröger base is reported; their potential application as conformationally restricted scaffolds is proposed and has been investigated using high level ab initio calculations. © The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)389-391
Number of pages3
JournalChemical Communications
Issue number4
DOIs
Publication statusPublished - 1 Jan 2007

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