Abstract
The reaction of (chloromethylene)dimethylammonium chloride (generated in situ from oxalyl chloride and DMF) with α-substituted ketones in CH2Cl2, followed by workup with aqueous NaHCO3, gave β-keto aldehydes containing an α-quaternary centre (8-88% yield).
| Original language | English |
|---|---|
| Pages (from-to) | 239-242 |
| Number of pages | 4 |
| Journal | Synlett |
| Volume | 2012 |
| Issue number | 02 |
| DOIs | |
| Publication status | Published - Jan 2012 |