(31)P magnetic resonance spectroscopy to measure in vivo cardiac energetics in normal myocardium and hypertrophic cardiomyopathy: Experiences at 3T

Ganesh Nallur Shivu, Khalid Abozguia, Thanh Trung Phan, Ibrar Ahmed, Anke Henning, Michael Frenneaux

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

(31)P magnetic resonance spectroscopy (MRS) allows measurement of in vivo high-energy phosphate kinetics in the myocardium. While traditionally (31)P cardiac spectroscopy is performed at 1.5T, cardiac MRS at higher field strength can theoretically increase signal to noise ratio (SNR) and spectral resolution therefore improving sensitivity and specificity of the cardiac spectra. The reproducibility and feasibility of performing cardiac spectroscopy at 3T is presented here in this study in healthy volunteers and patients with hypertrophic cardiomyopathy.
Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalEuropean Journal of Radiology
Volume73
Issue number2
DOIs
Publication statusPublished - 1 Feb 2010

Keywords

  • Cardiomyopathy, Hypertrophic
  • Humans
  • Magnetic Resonance Spectroscopy
  • Male
  • Middle Aged
  • Myocardium
  • Phosphates
  • Phosphorus Isotopes
  • Reproducibility of Results
  • Sensitivity and Specificity

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