32 Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure model predicts outcomes in heart failure: a multi-centre study

Ciaran Grafton-Clarke; Gareth Matthews; Rui Li; Hosamadin Assadi; Peter Swoboda; Chris Sawh; Vassilios S. Vassiliou; Andrew J. Swift; Pankaj Garg

32 Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure model predicts outcomes in heart failure: a multi-centre study

Ciaran Grafton-Clarke, Gareth Matthews, Rui Li, Hosamadin Assadi, Peter Swoboda, Chris Sawh, Vassilios S. Vassiliou, Andrew J. Swift, Pankaj Garg

Research output: Contribution to journal › Abstract › peer-review

Abstract

Non-invasive imaging is routinely used to estimate left ventricular (LV) filling pressure (LVFP) in heart failure (HF). Cardiovascular magnetic resonance (CMR) is emerging as an important imaging tool for sub-phenotyping HF and estimating pulmonary capillary wedge pressure (PCWP), a surrogate for LVFP.

This research sought to investigate the following questions:
1) Does sex (male/female) influence CMR-derived PCWP?
2) Compared to a previously validated generic CMR-derived PCWP model,1 does the use of a sex-specific model improve precision?
3) Is a novel sex-specific CMR-modelled PCWP prognostically significant?

Original language	English
Pages (from-to)	A27-A28
Number of pages	2
Journal	Heart
Volume	110
Issue number	Suppl 1
Publication status	Published - 11 Mar 2024

Access to Document

https://heart.bmj.com/content/110/Suppl_1/A27Licence: Unspecified

Cite this

@article{ec03adfa7a2247ffb7a82c4a63f1c294,

title = "32 Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure model predicts outcomes in heart failure: a multi-centre study",

abstract = "Non-invasive imaging is routinely used to estimate left ventricular (LV) filling pressure (LVFP) in heart failure (HF). Cardiovascular magnetic resonance (CMR) is emerging as an important imaging tool for sub-phenotyping HF and estimating pulmonary capillary wedge pressure (PCWP), a surrogate for LVFP. This research sought to investigate the following questions: 1) Does sex (male/female) influence CMR-derived PCWP? 2) Compared to a previously validated generic CMR-derived PCWP model,1 does the use of a sex-specific model improve precision? 3) Is a novel sex-specific CMR-modelled PCWP prognostically significant?",

author = "Ciaran Grafton-Clarke and Gareth Matthews and Rui Li and Hosamadin Assadi and Peter Swoboda and Chris Sawh and Vassiliou, {Vassilios S.} and Swift, {Andrew J.} and Pankaj Garg",

year = "2024",

month = mar,

day = "11",

language = "English",

volume = "110",

pages = "A27--A28",

journal = "Heart",

issn = "1355-6037",

publisher = "BMJ Publishing Group",

number = "Suppl 1",

}

32 Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure model predicts outcomes in heart failure: a multi-centre study. / Grafton-Clarke, Ciaran ; Matthews, Gareth ; Li, Rui ; Assadi, Hosamadin; Swoboda, Peter; Sawh, Chris; Vassiliou, Vassilios S.; Swift, Andrew J.; Garg, Pankaj.

In: Heart, Vol. 110, No. Suppl 1, 11.03.2024, p. A27-A28.

Research output: Contribution to journal › Abstract › peer-review

TY - JOUR

T1 - 32 Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure model predicts outcomes in heart failure: a multi-centre study

AU - Grafton-Clarke, Ciaran

AU - Matthews, Gareth

AU - Li, Rui

AU - Assadi, Hosamadin

AU - Swoboda, Peter

AU - Sawh, Chris

AU - Vassiliou, Vassilios S.

AU - Swift, Andrew J.

AU - Garg, Pankaj

PY - 2024/3/11

Y1 - 2024/3/11

N2 - Non-invasive imaging is routinely used to estimate left ventricular (LV) filling pressure (LVFP) in heart failure (HF). Cardiovascular magnetic resonance (CMR) is emerging as an important imaging tool for sub-phenotyping HF and estimating pulmonary capillary wedge pressure (PCWP), a surrogate for LVFP. This research sought to investigate the following questions: 1) Does sex (male/female) influence CMR-derived PCWP? 2) Compared to a previously validated generic CMR-derived PCWP model,1 does the use of a sex-specific model improve precision? 3) Is a novel sex-specific CMR-modelled PCWP prognostically significant?

AB - Non-invasive imaging is routinely used to estimate left ventricular (LV) filling pressure (LVFP) in heart failure (HF). Cardiovascular magnetic resonance (CMR) is emerging as an important imaging tool for sub-phenotyping HF and estimating pulmonary capillary wedge pressure (PCWP), a surrogate for LVFP. This research sought to investigate the following questions: 1) Does sex (male/female) influence CMR-derived PCWP? 2) Compared to a previously validated generic CMR-derived PCWP model,1 does the use of a sex-specific model improve precision? 3) Is a novel sex-specific CMR-modelled PCWP prognostically significant?

M3 - Abstract

VL - 110

SP - A27-A28

JO - Heart

JF - Heart

SN - 1355-6037

IS - Suppl 1

ER -