45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study

Linda P Hunt; Yoav Ben-Shlomo; Emma M Clark; Paul Dieppe; Andrew Judge; Alex J MacGregor; Jon H Tobias; Kelly Vernon; Ashley W Blom; on behalf of the National Joint Registry for England and Wales; Alexander Macgregor

doi:10.1016/S0140-6736(14)60540-7

45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study

Linda P Hunt, Yoav Ben-Shlomo, Emma M Clark, Paul Dieppe, Andrew Judge, Alex J MacGregor, Jon H Tobias, Kelly Vernon, Ashley W Blom, on behalf of the National Joint Registry for England and Wales, Alexander Macgregor

Research output: Contribution to journal › Article › peer-review

148 Citations (Scopus)

Abstract

Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded could be explained by alterations in modifiable perioperative factors.

Original language	English
Pages (from-to)	1429–1436
Number of pages	8
Journal	Lancet
Volume	384
Issue number	9952
Early online date	7 Jul 2014
DOIs	https://doi.org/10.1016/S0140-6736(14)60540-7
Publication status	Published - Oct 2014

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10.1016/S0140-6736(14)60540-7

Alexander Macgregor
- A.Macgregoruea.acuk
- Norwich Medical School - Professor of Genetic Epidemiology
- Norwich Institute for Healthy Aging - Member
- Norwich Epidemiology Centre - Member
- Epidemiology and Public Health - Member
- Musculoskeletal Medicine - Member
- Nutrition and Preventive Medicine - Member
Person: Group Lead, Research Group Member, Research Centre Member, Academic, Teaching & Research

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Hunt, L. P., Ben-Shlomo, Y., Clark, E. M., Dieppe, P., Judge, A., MacGregor, A. J., Tobias, J. H., Vernon, K., Blom, A. W., on behalf of the National Joint Registry for England and Wales, & Macgregor, A. (2014). 45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study. Lancet, 384(9952), 1429–1436. https://doi.org/10.1016/S0140-6736(14)60540-7

Hunt, Linda P ; Ben-Shlomo, Yoav ; Clark, Emma M ; Dieppe, Paul ; Judge, Andrew ; MacGregor, Alex J ; Tobias, Jon H ; Vernon, Kelly ; Blom, Ashley W ; on behalf of the National Joint Registry for England and Wales ; Macgregor, Alexander. / 45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales : an observational study. In: Lancet. 2014 ; Vol. 384, No. 9952. pp. 1429–1436.

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abstract = "Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded could be explained by alterations in modifiable perioperative factors.",

author = "Hunt, {Linda P} and Yoav Ben-Shlomo and Clark, {Emma M} and Paul Dieppe and Andrew Judge and MacGregor, {Alex J} and Tobias, {Jon H} and Kelly Vernon and Blom, {Ashley W} and {on behalf of the National Joint Registry for England and Wales} and Alexander Macgregor",

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Hunt, LP, Ben-Shlomo, Y, Clark, EM, Dieppe, P, Judge, A, MacGregor, AJ, Tobias, JH, Vernon, K, Blom, AW, on behalf of the National Joint Registry for England and Wales & Macgregor, A 2014, '45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study', Lancet, vol. 384, no. 9952, pp. 1429–1436. https://doi.org/10.1016/S0140-6736(14)60540-7

45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales : an observational study. / Hunt, Linda P; Ben-Shlomo, Yoav; Clark, Emma M; Dieppe, Paul; Judge, Andrew; MacGregor, Alex J; Tobias, Jon H; Vernon, Kelly; Blom, Ashley W; on behalf of the National Joint Registry for England and Wales ; Macgregor, Alexander.

In: Lancet, Vol. 384, No. 9952, 10.2014, p. 1429–1436.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - 45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales

T2 - an observational study

AU - Hunt, Linda P

AU - Ben-Shlomo, Yoav

AU - Clark, Emma M

AU - Dieppe, Paul

AU - Judge, Andrew

AU - MacGregor, Alex J

AU - Tobias, Jon H

AU - Vernon, Kelly

AU - Blom, Ashley W

AU - on behalf of the National Joint Registry for England and Wales

AU - Macgregor, Alexander

PY - 2014/10

Y1 - 2014/10

N2 - Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded could be explained by alterations in modifiable perioperative factors.

AB - Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded could be explained by alterations in modifiable perioperative factors.

U2 - 10.1016/S0140-6736(14)60540-7

DO - 10.1016/S0140-6736(14)60540-7

M3 - Article

C2 - 25012118

VL - 384

SP - 1429

EP - 1436

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9952

ER -

45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study

Abstract

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Alexander Macgregor

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