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Update of P2X receptor properties and their pharmacology: IUPHAR Review 30
Illes, P., Müller, C. E., Jacobson, K. A., Grutter, T., Nicke, A., Fountain, S. J., Kennedy, C., Schmalzing, G., Jarvis, M. F., Stojilkovic, S. S., King, B. F. & Di Virgilio, F., Feb 2021, In: British Journal of Pharmacology. 178, 3, p. 489-514 26 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile203 Citations (SciVal)17 Downloads (Pure) -
Extensions to in silico bioactivity predictions using pathway annotations and differential pharmacology analysis: Application to Xenopus laevis phenotypic readouts
Liggi, S., Drakakis, G., Hendry, A. E., Hanson, K. M., Brewerton, S. C., Wheeler, G. N., Bodkin, M. J., Evans, D. A. & Bender, A., Dec 2013, In: Molecular Informatics. 32, 11-12, p. 1009-1024 16 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Self-assembling, supramolecular chemistry and pharmacology of amphotericin B: Poly-aggregates, oligomers and monomers
Fernández-García, R., Muñoz-García, J. C., Wallace, M., Fabian, L., González-Burgos, E., Gómez-Serranillos, M. P., Raposo, R., Bolás-Fernández, F., Ballesteros, M. P., Healy, A. M., Khimyak, Y. Z. & Serrano, D. R., Jan 2022, In: Journal of Controlled Release. 341, p. 716-732 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)36 Downloads (Pure) -
Deciphering the potential of Cymbopogon citratus (DC.) Stapf as an anti-obesity agent: phytochemical profiling, in vivo evaluations and molecular docking studies
Aly, O., Mekky, R. H., Pereira, F., Diab, Y. M., Tammam, M. A. & El-Demerdash, A., 21 Dec 2024, In: Food & Function. 15, 24, p. 12146-12168 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Synthesis, structure and cytotoxicity of cyclic (alkyl)(amino) carbene and acyclic carbene complexes of group 11 metals
Bertrand, B., Romanov, A. S., Brooks, M., Schmidt, C., Ott, I., O'Connell, M. A. & Bochmann, M., 23 Oct 2017, In: Dalton Transactions. 46, p. 15875-15887 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (SciVal)18 Downloads (Pure) -
Discovery of 1-benzhydryl-piperazine-based HDAC inhibitors with anti-breast cancer activity: Synthesis, molecular modeling, in vitro and in vivo biological evaluation
Ruzic, D., Ellinger, B., Djokovic, N., Santibanez, J. F., Gul, S., Beljkas, M., Djuric, A., Ganesan, A., Pavic, A., Srdic-Rajic, T., Petkovic, M. & Nikolic, K., Dec 2022, In: Pharmaceutics. 14, 12, 2600.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)1 Downloads (Pure) -
The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism
Crichton, P. G., Lee, Y. & Kunji, E. R. S., Mar 2017, In: Biochimie. 134, p. 35–50 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile103 Citations (SciVal)51 Downloads (Pure) -
Emerging molecular mechanisms and genetic targets for developing novel therapeutic strategies for treating bladder diseases
Zoqlam, R., Lazauskaite, S., Glickman, S., Zaitseva, L., Ilie, P-C. & Qi, S., 1 Jun 2022, In: European Journal of Pharmaceutical Sciences. 173, 106167.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)20 Downloads (Pure) -
The impact of long chain n-3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an inflammatory phenotype
Browning, L. M., Krebs, J. D., Moore, C. S., Mishra, G. D., O'Connell, M. A. & Jebb, S. A., Jan 2007, In: Diabetes, Obesity & Metabolism. 9, 1, p. 70-80 11 p.Research output: Contribution to journal › Article › peer-review
135 Citations (Scopus) -
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
Cooper, C. S., Eeles, R. A., Wedge, D. C., Van Loo, P., Gundem, G., Alexandrov, L. B., Kreymer, B., Butler, A., Lynch, A., Edwards, S. E., Camacho, N., Massie, C. E., Kote-Jarai, Z., Dennis, N., Merson, S., Leongamornlert, D. A., Zamora, J., Kay, J., Luxton, H. J., Corbishley, C., & 53 others , Apr 2015, In: Nature Genetics. 47, p. 367–372 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile328 Citations (Scopus)17 Downloads (Pure) -
Core shell lipid-polymer hybrid nanoparticles with combined docetaxel and molecular targeted therapy for the treatment of metastatic prostate cancer
Wang, Q., Alshaker, H., Böhler, T., Srivats, S., Chao, Y., Cooper, C. & Pchejetski, D., 19 Jul 2017, In: Scientific Reports. 7, 5901.Research output: Contribution to journal › Article › peer-review
Open AccessFile66 Citations (SciVal)44 Downloads (Pure) -
Molecular determinants of the cardiometabolic improvements of dietary flavanols identified by an integrative analysis of nutrigenomic data from a systematic review of animal studies
Monfoulet, L-E., Ruskovska, T., Ajdzanovic, V., Havlik, J., Vauzour, D., Bayram, B., Krga, I., Fabiola, C. J. K., Kistanova, E., Abadjieva, D., Massaro, M., Scodetti, E., Deligiannidou, E., Kontogiorgis, C., Arola-Arnal, A., van Schothorst, E. M., Morand, C. & Milenkovic, D., Aug 2021, In: Molecular Nutrition & Food Research. 65, 16, 2100227.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (SciVal)9 Downloads (Pure) -
Herbaceous homicide: The Panax ginseng metabolite compound K accelerates caspase-3/7 activation and enhances macrophage cell death in a P2X7-dependent manner
Bidula, S., Dhuna, K., Helliwell, R., Stebbing, M. & Stokes, L., Aug 2019, In: British Journal of Pharmacology. 176, 16, p. 3028-3028 1 p.Research output: Contribution to journal › Abstract › peer-review
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The role of PKC in CXCL8 and CXCL10 directed prostate, breast and leukemic cancer cell migration
Al Assaf, E. & Mueller, A., 5 Nov 2020, In: European Journal of Pharmacology. 886, 173453.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (SciVal)12 Downloads (Pure) -
Revisiting the past to enhance the future: Traditional medicinal plant extracts in the discovery of novel drug lead to target P2X7
Bidula, S., Bibic, L., Moulton, A., Zhang, J. & Stokes, L., Jun 2020, In: British Journal of Pharmacology. 177, 11, p. 2628-2629 2 p.Research output: Contribution to journal › Abstract › peer-review
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To inhibit or enhance? Is there a benefit to positive allosteric modulation of P2X receptors?
Stokes, L., Bidula, S., Bibič, L. & Allum, E., 12 May 2020, In: Frontiers in Pharmacology. 11, 627.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)29 Downloads (Pure) -
Ginsenosides act as positive modulators of P2X4 receptors
Dhuna, K., Felgate, M., Bidula, S., Walpole, S., Bibic, L., Cromer, B., Angulo, J., Sanderson, J., Stebbing, M. & Stokes, L., Jan 2019, In: Molecular Pharmacology. 95, 2, p. 210-221 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (SciVal)21 Downloads (Pure) -
Pharmacological and genetic characterisation of the canine P2X4 receptor
Sophocleous, R. A., Berg, T., Finol‐Urdaneta, R. K., Sluyter, V., Keshiya, S., Bell, L., Curtis, S. J., Curtis, B. L., Seavers, A., Bartlett, R., Dowton, M., Stokes, L., Ooi, L. & Sluyter, R., Jun 2020, In: British Journal of Pharmacology. 177, 12, p. 2812-2829 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)32 Downloads (Pure) -
Immunomodulatory effects of 1, 25 (OH)2 D-3 in normal and transformed human lung epithelium
Norton, R., Sexton, D. W., Clark, I. M., Wilson, A. M., Hughes, D. A. & O'Connell, M. A., Apr 2011, In: Anticancer Research. 31, 4, p. 1499 1 p.Research output: Contribution to journal › Abstract
Open Access -
Anti-melanogenic potential of Malabar spinach (Basella Alba) in human melanoma cells with oxidative stress suppression and anti-inflammatory activities
Linsaenkart, P., Ruksiriwanich, W., Sringarm, K., Arjin, C., Rachtanapun, P., Chittasupho, C., Castagnini, J. M., Chutoprapat, R., Mueller, A. & Boonpisuttinant, K., 18 Sept 2024, In: Foods. 13, 18, 2943.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)8 Downloads (Pure) -
Design and synthesis of threading intercalators to target DNA
Howell, L., Gulam, R., Mueller, A., O'Connell, M. & Searcey, M., 7 Oct 2010, In: Bioorganic & Medicinal Chemistry Letters. 1, 20, p. 6956-6959 4 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Nucleotides regulate secretion of the inflammatory chemokine CCL2 from human macrophages and monocytes
Higgins, K. R., Kovacevic, W. & Stokes, L., 7 Sept 2014, In: Mediators of Inflammation. 2014, 13 p., 293925.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)17 Downloads (Pure) -
The development of potent, competitive CXCR4 antagonists for the prevention of cancer metastasis
Hamshaw, I., Cominetti, M. M. D., Lai, W-Y., Searcey, M. & Mueller, A., Dec 2023, In: Biochemical Pharmacology. 218, 115921.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors
Helliwell, R., ShioukHuey, C., Dhuna, K., Molero, J., Ye, J., Xue, C. & Stokes, L., Jul 2015, In: British Journal of Pharmacology. 172, 13, p. 3326-3340 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)12 Downloads (Pure) -
STAT1- and NFAT-independent amplification of purinoceptor function integrates cellular senescence with interleukin-6 production in preadipocytes
Majeed, Y., Madani, A. Y., Altamimi, A. I., Courjaret, R., Vakayil, M., Fountain, S. J., Machaca, K. & Mazloum, N. A., Mar 2023, In: British Journal of Pharmacology. 180, 5, p. 609-627 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure)