Abstract
A highly stereoselective iodocyclisation of the 3-alkene-1,2-diol 9, derived from asymmetric dihydroxylation of the dienyl benzoate 8, gives the β-iodotetrahydrofuran 10 and thence the Aplasmomycin precursor 13, following deiodination and Mitsunobu inversion. (C) 2000 Elsevier Science Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 4453-4456 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 41 |
| Issue number | 22 |
| Publication status | Published - 8 Jun 2000 |