A C-2-symmetric metallocene-pyrrolidinopyridine nucleophilic catalyst for asymmetric synthesis

H. V. Nguyen, M. Motevalli, C. J. Richards

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22 Citations (Scopus)


A C-2 -symmetric nucleophilic catalyst, (R,R)-3,5-diferrocenyl-4-(2',5'-dimethylpyrrolidino)pyridine, was synthesised in three steps from commercially available (S,S)-hexane-2,5-diol. Application to the kinetic resolution of secondary alcohols (0.5 mol% loading) resulted in selectivity factors (s) of up to 6.
Original languageEnglish
Pages (from-to)725-728
Number of pages4
Issue number5
Publication statusPublished - 2007

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