Projects per year
Abstract
BACKGROUND: Chronic rhinosinusitis (CRS) is a common and debilitating disorder. Little is known about the epidemiology of this disease. The aims of the study were to identify differences in socio-economic variables and quality of life between patients with chronic rhinosinusitis and healthy controls, to identify any significant associations between CRS and other medical co-morbidities, psychiatric disease or environmental exposure and to explore the experience of CRS from the perspective of CRS sufferers.
METHODS: Participants were recruited from ENT clinics from 30 centres across the UK. They completed a study-specific questionnaire considering environmental, medical and socio-economic factors, and SF-36 and SNOT-22 scores. All participants with CRS were diagnosed by a clinician and categorised as having CRS (with polyposis, without polyposis or allergic fungal rhinosinusitis (AFRS)). Controls included family and friends of those attending ENT outpatient clinics and hospital staff who had no diagnosis of nose or sinus problems and had not been admitted to hospital in the previous 12 months.
RESULTS: A total of 1470 study participants (1249 patients and 221 controls) were included in the final analysis. Highly significant differences were seen in generic and disease-specific quality of life scores between CRS sufferers and controls; mean SNOT-22 score 45.0 for CRS compared with 12.1 amongst controls. There were no clear differences in socioeconomic variables including social class, index of multiple deprivation and educational attainment between cases and controls. Common comorbidities with a clear association included respiratory and psychiatric disorders, with a higher frequency of reported upper respiratory tract infections.
CONCLUSIONS: CRS is associated with significant impairment in quality of life and with certain medical co-morbidities. In contrast to other common ENT disorders, no socioeconomic differences were found between patients and controls in this study.
METHODS: Participants were recruited from ENT clinics from 30 centres across the UK. They completed a study-specific questionnaire considering environmental, medical and socio-economic factors, and SF-36 and SNOT-22 scores. All participants with CRS were diagnosed by a clinician and categorised as having CRS (with polyposis, without polyposis or allergic fungal rhinosinusitis (AFRS)). Controls included family and friends of those attending ENT outpatient clinics and hospital staff who had no diagnosis of nose or sinus problems and had not been admitted to hospital in the previous 12 months.
RESULTS: A total of 1470 study participants (1249 patients and 221 controls) were included in the final analysis. Highly significant differences were seen in generic and disease-specific quality of life scores between CRS sufferers and controls; mean SNOT-22 score 45.0 for CRS compared with 12.1 amongst controls. There were no clear differences in socioeconomic variables including social class, index of multiple deprivation and educational attainment between cases and controls. Common comorbidities with a clear association included respiratory and psychiatric disorders, with a higher frequency of reported upper respiratory tract infections.
CONCLUSIONS: CRS is associated with significant impairment in quality of life and with certain medical co-morbidities. In contrast to other common ENT disorders, no socioeconomic differences were found between patients and controls in this study.
Original language | English |
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Pages (from-to) | 134-140 |
Number of pages | 7 |
Journal | Rhinology |
Volume | 54 |
Issue number | 2 |
Publication status | Published - 2016 |
Keywords
- Chronic rhinosinusitis
- health inequalities
- quality of life
- respiratory disease
- socioeconomic factors
Projects
- 1 Finished
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Clinical Senior Lectureship - Clinical Research Ear, Nose and Throat
Fraser, W., Harvey, I. & Philpott, C.
James Paget University Hospitals NHS Foundation Trust
1/01/10 → 31/03/20
Project: Research
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Evaluation of smoking as a modifying factor in chronic rhinosinusitis
Hutson, K., Clark, A., Hopkins, C., Ahmed, S., Kumar, N., Carrie, S., Erskine, S., Sunkaraneni, V., Philpott, C. & CRES group, Feb 2021, In: JAMA Otolaryngology-Head & Neck Surgery. 147, 2, p. 159-165 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (SciVal)18 Downloads (Pure) -
SNOT-22 in a control population
Erskine, S., Hopkins, C., Clark, A., Anari, S., Kumar, N., Robertson, A., Sunkaraneni, V., Wilson, J. A., Carrie, S., Kara, N., Ray, J., Smith, R., Philpott, C. & CRES group, Feb 2017, In: Clinical Otolaryngology. 42, 1, p. 81–85 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (SciVal)29 Downloads (Pure) -
Results of the Chronic Rhinosinusitis Epidemiology Study
Erskine, S., Philpott, C. & Clark, A., 2015.Research output: Contribution to conference › Abstract › peer-review
Datasets
Press/Media
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CRNE-Look-Eastern-March CRES News
1/01/15
1 Media contribution
Press/Media: Media Coverage or Contribution