A case of cerebellar medulloblastoma with a single chromosome abnormality

M. R. Stratton, J. Darling, C. S. Cooper, B. R. Reeves

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


In the few published karyotypes of human medulloblastoma, multiple chromosome abnormalities have usually been demonstrated. We report a case of medulloblastoma in which only a single structural alteration was observed, namely an unbalanced translocation between chromosomes 1 and 6 resulting in partial 1q trisomy and partial 6q mónosomy. This finding may help define genomic regions that are of importance in development of medulloblastoma.

Original languageEnglish
Pages (from-to)101-103
Number of pages3
JournalCancer Genetics and Cytogenetics
Issue number1
Publication statusPublished - 1 May 1991

Cite this