A convenient synthesis of chiral nonracemic vinyl aziridines

Daniel Morton; David Pearson; Robert A. Field; Robert A. Stockman

doi:10.1021/ol049252l

A convenient synthesis of chiral nonracemic vinyl aziridines

Daniel Morton, David Pearson, Robert A. Field, Robert A. Stockman

School of Chemistry, Pharmacy and Pharmacology

Research output: Contribution to journal › Article › peer-review

98 Citations (Scopus)

Abstract

The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.

Original language	English
Pages (from-to)	2377-2380
Number of pages	4
Journal	Organic Letters
Volume	6
Issue number	14
DOIs	https://doi.org/10.1021/ol049252l
Publication status	Published - 8 Jul 2004

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10.1021/ol049252l

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title = "A convenient synthesis of chiral nonracemic vinyl aziridines",

abstract = "The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.",

author = "Daniel Morton and David Pearson and Field, {Robert A.} and Stockman, {Robert A.}",

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AU - Pearson, David

AU - Field, Robert A.

AU - Stockman, Robert A.

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N2 - The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.

AB - The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.

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U2 - 10.1021/ol049252l

DO - 10.1021/ol049252l

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SP - 2377

EP - 2380

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 14

ER -

A convenient synthesis of chiral nonracemic vinyl aziridines

Abstract

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