A decade of antifungal leads from natural products: 2010-2019

Mohammed Aldholmi; Pascal Marchand; Isabelle Ourliac-Garnier; Patrice Le Pape; A. Ganesan

doi:10.3390/ph12040182

A decade of antifungal leads from natural products: 2010-2019

Mohammed Aldholmi, Pascal Marchand, Isabelle Ourliac-Garnier, Patrice Le Pape, A. Ganesan

Research output: Contribution to journal › Review article › peer-review

56 Citations (Scopus)

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Abstract

In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.

Original language	English
Article number	182
Journal	Pharmaceuticals
Volume	12
Issue number	4
DOIs	https://doi.org/10.3390/ph12040182
Publication status	Published - 12 Dec 2019

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10.3390/ph12040182Licence: CC BY

Published_VersionFinal published version, 6.47 MBLicence: CC BY

Cite this

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AB - In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.

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