Abstract
A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.
Original language | English |
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Pages (from-to) | 245-250 |
Number of pages | 6 |
Journal | Nature |
Volume | 346 |
Issue number | 6281 |
DOIs | |
Publication status | Published - 19 Jul 1990 |