A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3',5'-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans

Qingzhi Zhang, Nigel P Botting, Colin Kay

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The major dietary anthocyanin, cyanidin-3-glucoside, was prepared on a 4 g scale from three units of diethyl [2-(13)C]malonate and one unit of [1,3-(13)C(2)]acetone, such that five isotope locations were distributed throughout the molecule to provide a penta-(13)C(5)-labelled anthocyanin, [6,8,10,3',5'-(13)C(5)]cyanidin-3-glucoside chloride, for use in human stable-isotope tracer studies.
Original languageEnglish
Pages (from-to)10596-10598
Number of pages3
JournalChemical communications (Cambridge, England)
Volume47
Issue number38
DOIs
Publication statusPublished - 14 Oct 2011

Keywords

  • Administration, Oral
  • Anthocyanins
  • Carbon Isotopes
  • Glucosides
  • Humans
  • Isotope Labeling
  • Stereoisomerism

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