A legacy of tinnitus: multiple head and neck paragangliomas

Tricia M. M. Tan, Emma C. I. Hatfield, Rajesh V. Thakker, Eamonn R. Maher, Karim Meeran, Niamh M. Martin, Jeremy J. Turner

Research output: Contribution to journalArticle


We describe the case of a patient who presented with a right-sided glomus jugulare tumor and bilateral glomus vagale tumors. These proved to be nonmalignant paragangliomas on histopathological analysis. Genetic analysis revealed a germline heterozygous missense mutation (Pro81Leu) in the succinate dehydrogenase subunit D (SDHD) gene. We discuss the clinical presentations of the familial paraganglioma syndrome type 1, which is caused by mutations in SDHD, and the implications for the clinical diagnosis and care of such patients.
Original languageEnglish
Pages (from-to)88-89
Number of pages2
JournalRare Tumors
Issue number2
Publication statusPublished - 2009

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