A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy

J Stebbing, A Sharma, B North, T J Athersuch, A Zebrowski, D Pchejetski, R C Coombes, J K Nicholson, H C Keun

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

Breast cancer is associated with adverse outcomes in patients with the metabolic syndrome phenotype. To study this further, we examined the relationship between serum metabolite levels and the components of metabolic syndrome with treatment outcomes in breast cancer.
Original languageEnglish
Pages (from-to)860-866
Number of pages7
JournalAnnals of Oncology
Volume23
Issue number4
DOIs
Publication statusPublished - Apr 2012

Keywords

  • Adult
  • Aged
  • Aged 80 and over
  • Blood Glucose
  • Blood Pressure
  • Breast Neoplasms
  • Female
  • Humans
  • Logistic Models
  • Metabolic Syndrome X
  • Middle Aged
  • Multivariate Analysis
  • Phenotype
  • Postmenopause
  • Treatment Outcome
  • Triglycerides

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