A new dihydrodibenzodioxinone from Hypericum x 'Hidcote'

Longru Sun; M. Mukhlesur Rahman; Brian W. Skelton; Simon Gibbons

doi:10.1016/j.fitote.2009.01.012

A new dihydrodibenzodioxinone from Hypericum x 'Hidcote'

Longru Sun, M. Mukhlesur Rahman, Brian W. Skelton, Simon Gibbons

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

One new compound, 4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one (1), was isolated from the aerial parts of the hybrid Hypericum x ‘Hidcote’, together with 8 known compounds: caryophyllene-4,5-epoxide, quercetin, quercitrin, quercetin-3-O-β-D-galactopyranoside, epicatechin, betulinic acid methyl ester, β-sitosterol and β-sitosterol glucoside. The structure of the new compound, as well as its absolute configuration, was established by means of spectroscopic data analyses, including 2D NMR spectroscopy and X-ray structural analysis.

Original language	English
Pages (from-to)	226-229
Number of pages	4
Journal	Fitoterapia
Volume	80
Issue number	4
Early online date	2 Feb 2009
DOIs	https://doi.org/10.1016/j.fitote.2009.01.012
Publication status	Published - Jun 2009

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10.1016/j.fitote.2009.01.012

Cite this

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title = "A new dihydrodibenzodioxinone from Hypericum x 'Hidcote'",

abstract = "One new compound, 4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one (1), was isolated from the aerial parts of the hybrid Hypericum x {\textquoteleft}Hidcote{\textquoteright}, together with 8 known compounds: caryophyllene-4,5-epoxide, quercetin, quercitrin, quercetin-3-O-β-D-galactopyranoside, epicatechin, betulinic acid methyl ester, β-sitosterol and β-sitosterol glucoside. The structure of the new compound, as well as its absolute configuration, was established by means of spectroscopic data analyses, including 2D NMR spectroscopy and X-ray structural analysis.",

author = "Longru Sun and Rahman, {M. Mukhlesur} and Skelton, {Brian W.} and Simon Gibbons",

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AU - Sun, Longru

AU - Rahman, M. Mukhlesur

AU - Skelton, Brian W.

AU - Gibbons, Simon

PY - 2009/6

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N2 - One new compound, 4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one (1), was isolated from the aerial parts of the hybrid Hypericum x ‘Hidcote’, together with 8 known compounds: caryophyllene-4,5-epoxide, quercetin, quercitrin, quercetin-3-O-β-D-galactopyranoside, epicatechin, betulinic acid methyl ester, β-sitosterol and β-sitosterol glucoside. The structure of the new compound, as well as its absolute configuration, was established by means of spectroscopic data analyses, including 2D NMR spectroscopy and X-ray structural analysis.

AB - One new compound, 4-hydroxy-4a,7-dimethoxy-4,4a-dihydrodibenzo-p-dioxin-2(3H)-one (1), was isolated from the aerial parts of the hybrid Hypericum x ‘Hidcote’, together with 8 known compounds: caryophyllene-4,5-epoxide, quercetin, quercitrin, quercetin-3-O-β-D-galactopyranoside, epicatechin, betulinic acid methyl ester, β-sitosterol and β-sitosterol glucoside. The structure of the new compound, as well as its absolute configuration, was established by means of spectroscopic data analyses, including 2D NMR spectroscopy and X-ray structural analysis.

U2 - 10.1016/j.fitote.2009.01.012

DO - 10.1016/j.fitote.2009.01.012

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EP - 229

JO - Fitoterapia

JF - Fitoterapia

SN - 0367-326X

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