A new role for Ran in ensuring precise duplication of chromosomal DNA

J. Julian Blow

doi:10.1016/S0092-8674(03)00236-8

A new role for Ran in ensuring precise duplication of chromosomal DNA

J. Julian Blow

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.

Original language	English
Pages (from-to)	2-4
Number of pages	3
Journal	Cell
Volume	113
Issue number	1
DOIs	https://doi.org/10.1016/S0092-8674(03)00236-8
Publication status	Published - 4 Apr 2003

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10.1016/S0092-8674(03)00236-8Licence: Other

Cite this

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title = "A new role for Ran in ensuring precise duplication of chromosomal DNA",

abstract = "To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.",

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AB - To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.

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