A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer

H. Tehrani; J. Walls; G. M. Price; S. Cotton; E. Sassoon; P. Hall

doi:10.1111/j.1365-2133.2006.07513.x

A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer

H. Tehrani, J. Walls, G. M. Price, S. Cotton, E. Sassoon, P. Hall

Research output: Contribution to journal › Article

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Abstract

Background: Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC).

Objectives: A prospective study was conducted to investigate the potential for the SIAscope to diagnose NMSC.

Methods: In total, 302 consecutive patients were recruited into the study, 363 lesions being scanned. Logistic regression analysis was used to construct a predictive model for NMSC diagnosis and receiver–operator characteristic curves were used to assess overall accuracy of the model.

Results: A sensitivity of 98·0%, specificity of 95·7% and overall accuracy of 98·2% was found for NMSC diagnosis by the SIAscope model.

Conclusions: Results suggest that the SIAscope may be a useful adjunct in the diagnosis of NMSC.

Original language	English
Pages (from-to)	1177-1183
Number of pages	7
Journal	British Journal of Dermatology
Volume	155
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2133.2006.07513.x
Publication status	Published - Dec 2006

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10.1111/j.1365-2133.2006.07513.x

Cite this

@article{70e811c523484f82a1120fdce559de32,

title = "A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer",

abstract = "Background: Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC). Objectives: A prospective study was conducted to investigate the potential for the SIAscope to diagnose NMSC. Methods: In total, 302 consecutive patients were recruited into the study, 363 lesions being scanned. Logistic regression analysis was used to construct a predictive model for NMSC diagnosis and receiver–operator characteristic curves were used to assess overall accuracy of the model. Results: A sensitivity of 98·0%, specificity of 95·7% and overall accuracy of 98·2% was found for NMSC diagnosis by the SIAscope model. Conclusions: Results suggest that the SIAscope may be a useful adjunct in the diagnosis of NMSC.",

author = "H. Tehrani and J. Walls and Price, {G. M.} and S. Cotton and E. Sassoon and P. Hall",

year = "2006",

month = dec,

doi = "10.1111/j.1365-2133.2006.07513.x",

language = "English",

volume = "155",

pages = "1177--1183",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Wiley",

number = "6",

}

TY - JOUR

T1 - A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer

AU - Tehrani, H.

AU - Walls, J.

AU - Price, G. M.

AU - Cotton, S.

AU - Sassoon, E.

AU - Hall, P.

PY - 2006/12

Y1 - 2006/12

N2 - Background: Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC). Objectives: A prospective study was conducted to investigate the potential for the SIAscope to diagnose NMSC. Methods: In total, 302 consecutive patients were recruited into the study, 363 lesions being scanned. Logistic regression analysis was used to construct a predictive model for NMSC diagnosis and receiver–operator characteristic curves were used to assess overall accuracy of the model. Results: A sensitivity of 98·0%, specificity of 95·7% and overall accuracy of 98·2% was found for NMSC diagnosis by the SIAscope model. Conclusions: Results suggest that the SIAscope may be a useful adjunct in the diagnosis of NMSC.

AB - Background: Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC). Objectives: A prospective study was conducted to investigate the potential for the SIAscope to diagnose NMSC. Methods: In total, 302 consecutive patients were recruited into the study, 363 lesions being scanned. Logistic regression analysis was used to construct a predictive model for NMSC diagnosis and receiver–operator characteristic curves were used to assess overall accuracy of the model. Results: A sensitivity of 98·0%, specificity of 95·7% and overall accuracy of 98·2% was found for NMSC diagnosis by the SIAscope model. Conclusions: Results suggest that the SIAscope may be a useful adjunct in the diagnosis of NMSC.

U2 - 10.1111/j.1365-2133.2006.07513.x

DO - 10.1111/j.1365-2133.2006.07513.x

M3 - Article

VL - 155

SP - 1177

EP - 1183

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

IS - 6

ER -