A novel, spontaneously immortalized, human prostate cancer cell line, Bob, offers a unique model for pre-clinical prostate cancer studies

Gerhardt Attard, Sian Rizzo, Ioanna Ledaki, Jeremy Clark, Alison H M Reid, Alan Thompson, Vincent Khoo, Johann S de Bono, Colin S Cooper, David L Hudson

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


New in vitro models of castration-resistant prostate cancer (CRPC) are urgently required.
Original languageEnglish
Pages (from-to)1507-20
Number of pages14
JournalThe Prostate
Issue number14
Publication statusPublished - 1 Oct 2009


  • Animals
  • Biopsy, Needle
  • Blood Proteins
  • Cell Adhesion
  • Cell Culture Techniques
  • Cell Differentiation
  • Cell Division
  • Cell Line, Transformed
  • Cell Line, Tumor
  • Cell Movement
  • Cell Separation
  • Comparative Genomic Hybridization
  • DNA, Neoplasm
  • Eukaryotic Initiation Factor-3
  • Humans
  • Karyotyping
  • Male
  • Methylcellulose
  • Mice
  • Mice, SCID
  • Neoplasm Transplantation
  • Phenotype
  • Prostatic Neoplasms
  • Spheroids, Cellular

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