A polar cannabinoid from Cannabis sativa var. Carma

Giovanni Appendino, Anna Giana, Simon Gibbons, Massimo Maffei, Giorgio Gnavi, Gianpaolo Grassi, Olov Sterner

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26 Citations (Scopus)


The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

Original languageEnglish
Pages (from-to)1977-1980
Number of pages4
JournalNatural Product Communications
Issue number12
Publication statusPublished - 1 Dec 2008


  • Cannabis sativa
  • Cannabinaceae
  • carmagerol
  • cannabigerol
  • antibacterial activity

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