A Polar Cannabinoid from Cannabis sativa var. Carma

Giovanni Appendino; Anna Giana; Simon Gibbons; Massimo Maffei; Giorgio Gnavi; Gianpaolo Grassi; Olov Sterner

doi:10.1177/1934578X0800301207

A Polar Cannabinoid from Cannabis sativa var. Carma

Giovanni Appendino, Anna Giana, Simon Gibbons, Massimo Maffei, Giorgio Gnavi, Gianpaolo Grassi, Olov Sterner

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

Original language	English
Pages (from-to)	1977-1980
Number of pages	4
Journal	Natural Product Communications
Volume	3
Issue number	12
DOIs	https://doi.org/10.1177/1934578X0800301207
Publication status	Published - 1 Dec 2008

Keywords

Cannabis sativa
Cannabinaceae
carmagerol
cannabigerol
antibacterial activity
CONSTITUENTS

Access to Document

10.1177/1934578X0800301207

Cite this

@article{86d3870f29d748a2ad1671df6a45d6c3,

title = "A Polar Cannabinoid from Cannabis sativa var. Carma",

abstract = "The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.",

keywords = "Cannabis sativa, Cannabinaceae, carmagerol, cannabigerol, antibacterial activity, CONSTITUENTS",

author = "Giovanni Appendino and Anna Giana and Simon Gibbons and Massimo Maffei and Giorgio Gnavi and Gianpaolo Grassi and Olov Sterner",

year = "2008",

month = dec,

day = "1",

doi = "10.1177/1934578X0800301207",

language = "English",

volume = "3",

pages = "1977--1980",

journal = "Natural Product Communications",

issn = "1934-578X",

publisher = "Sage Publications",

number = "12",

}

TY - JOUR

T1 - A Polar Cannabinoid from Cannabis sativa var. Carma

AU - Appendino, Giovanni

AU - Giana, Anna

AU - Gibbons, Simon

AU - Maffei, Massimo

AU - Gnavi, Giorgio

AU - Grassi, Gianpaolo

AU - Sterner, Olov

PY - 2008/12/1

Y1 - 2008/12/1

N2 - The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

AB - The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

KW - Cannabis sativa

KW - Cannabinaceae

KW - carmagerol

KW - cannabigerol

KW - antibacterial activity

KW - CONSTITUENTS

U2 - 10.1177/1934578X0800301207

DO - 10.1177/1934578X0800301207

M3 - Article

VL - 3

SP - 1977

EP - 1980

JO - Natural Product Communications

JF - Natural Product Communications

SN - 1934-578X

IS - 12

ER -