A polar cannabinoid from Cannabis sativa var. Carma

Giovanni Appendino; Anna Giana; Simon Gibbons; Massimo Maffei; Giorgio Gnavi; Gianpaolo Grassi; Olov Sterner

doi:10.1177/1934578X0800301207

A polar cannabinoid from Cannabis sativa var. Carma

Giovanni Appendino, Anna Giana, Simon Gibbons, Massimo Maffei, Giorgio Gnavi, Gianpaolo Grassi, Olov Sterner

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

Original language	English
Pages (from-to)	1977-1980
Number of pages	4
Journal	Natural Product Communications
Volume	3
Issue number	12
DOIs	https://doi.org/10.1177/1934578X0800301207
Publication status	Published - 1 Dec 2008

Keywords

Cannabis sativa
Cannabinaceae
carmagerol
cannabigerol
antibacterial activity
CONSTITUENTS

Access to Document

10.1177/1934578X0800301207

Cite this

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title = "A polar cannabinoid from Cannabis sativa var. Carma",

abstract = "The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.",

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AU - Appendino, Giovanni

AU - Giana, Anna

AU - Gibbons, Simon

AU - Maffei, Massimo

AU - Gnavi, Giorgio

AU - Grassi, Gianpaolo

AU - Sterner, Olov

PY - 2008/12/1

Y1 - 2008/12/1

N2 - The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

AB - The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

KW - Cannabis sativa

KW - Cannabinaceae

KW - carmagerol

KW - cannabigerol

KW - antibacterial activity

KW - CONSTITUENTS

U2 - 10.1177/1934578X0800301207

DO - 10.1177/1934578X0800301207

M3 - Article

SN - 1934-578X

VL - 3

SP - 1977

EP - 1980

JO - Natural Product Communications

JF - Natural Product Communications

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