A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery

Natasha E Khan; Anthony De Souza; Rebecca Mister; Marcus Flather; Jonathan Clague; Simon Davies; Peter Collins; Duolao Wang; Ulrich Sigwart; John Pepper

doi:10.1056/NEJMoa031282

A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery

Natasha E Khan
, Anthony De Souza
, Rebecca Mister
, Marcus Flather
, Jonathan Clague
, Simon Davies
, Peter Collins
, Duolao Wang
, Ulrich Sigwart
, John Pepper

Research output: Contribution to journal › Article › peer-review

517 Citations (Scopus)

Abstract

The effect of the use of coronary-artery bypass surgery without cardiopulmonary bypass and cardiac arrest ("off pump") on graft patency remains uncertain. We undertook a prospective, randomized, controlled study to compare graft-patency rates and clinical outcomes in off-pump surgery with conventional, "on-pump" surgery.

Original language	English
Pages (from-to)	21-8
Number of pages	8
Journal	New England Journal of Medicine
Volume	350
Issue number	1
DOIs	https://doi.org/10.1056/NEJMoa031282
Publication status	Published - 1 Jan 2004

Keywords

Aged
Area Under Curve
Cardiopulmonary Bypass
Coronary Angiography
Coronary Artery Bypass
Coronary Disease
Coronary Stenosis
Coronary Vessels
Female
Heart-Lung Machine
Humans
Length of Stay
Male
Middle Aged
Postoperative Complications
Prospective Studies
Troponin T
Vascular Patency

Access to Document

10.1056/NEJMoa031282

Cite this

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abstract = "The effect of the use of coronary-artery bypass surgery without cardiopulmonary bypass and cardiac arrest ({"}off pump{"}) on graft patency remains uncertain. We undertook a prospective, randomized, controlled study to compare graft-patency rates and clinical outcomes in off-pump surgery with conventional, {"}on-pump{"} surgery.",

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AU - Khan, Natasha E

AU - De Souza, Anthony

AU - Mister, Rebecca

AU - Flather, Marcus

AU - Clague, Jonathan

AU - Davies, Simon

AU - Collins, Peter

AU - Wang, Duolao

AU - Sigwart, Ulrich

AU - Pepper, John

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KW - Coronary Disease

KW - Coronary Stenosis

KW - Coronary Vessels

KW - Female

KW - Heart-Lung Machine

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KW - Length of Stay

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