A review: Synthesis and medicinal importance of coumarins and their analogues (part ii)

Moustafa A. Gouda; Belal H.M. Hussein; Amr El-Demerdash; Mona E. Ibrahim; Mohammed A. Salem; Mohamed H. Helal; Wafaa S. Hamama

doi:10.2174/1573407215666191111120604

A review: Synthesis and medicinal importance of coumarins and their analogues (part ii)

Moustafa A. Gouda, Belal H.M. Hussein, Amr El-Demerdash, Mona E. Ibrahim, Mohammed A. Salem, Mohamed H. Helal, Wafaa S. Hamama

Research output: Contribution to journal › Review article › peer-review

14 Citations (Scopus)

Abstract

Coumarins are a set of polyphenolic compounds isolated from plant product tonka bean, cou-marou in 1820. They belong to the family of benzopyrones, which includes benzene ring joined with the aid of a pyrone ring. Coumarins have attracted great attention of medicinal chemists and pharmacologists in recent years as they been confirmed to bear diverse pharmacological activities like anti-inflammatory and analgesic, anti oxidant, anticancer, etc. This review highlights the method of preparation, chemical reactivity, and organic properties such as anti-inflammatory, anticoagulant, antioxidant, anticancer and analgesic activities, of coumarins and their analogues.

Original language	English
Pages (from-to)	993-1008
Number of pages	16
Journal	Current Bioactive Compounds
Volume	16
Issue number	7
DOIs	https://doi.org/10.2174/1573407215666191111120604
Publication status	Published - 2020

Keywords

Anti-inflammatory and analgesic activity
Anticoagulant activity
Antioxidant and anticancer activity
Chloroacetyl chloride
Coumarins
Synthesis

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10.2174/1573407215666191111120604

Cite this

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abstract = "Coumarins are a set of polyphenolic compounds isolated from plant product tonka bean, cou-marou in 1820. They belong to the family of benzopyrones, which includes benzene ring joined with the aid of a pyrone ring. Coumarins have attracted great attention of medicinal chemists and pharmacologists in recent years as they been confirmed to bear diverse pharmacological activities like anti-inflammatory and analgesic, anti oxidant, anticancer, etc. This review highlights the method of preparation, chemical reactivity, and organic properties such as anti-inflammatory, anticoagulant, antioxidant, anticancer and analgesic activities, of coumarins and their analogues.",

keywords = "Anti-inflammatory and analgesic activity, Anticoagulant activity, Antioxidant and anticancer activity, Chloroacetyl chloride, Coumarins, Synthesis",

author = "Gouda, {Moustafa A.} and Hussein, {Belal H.M.} and Amr El-Demerdash and Ibrahim, {Mona E.} and Salem, {Mohammed A.} and Helal, {Mohamed H.} and Hamama, {Wafaa S.}",

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T2 - Synthesis and medicinal importance of coumarins and their analogues (part ii)

AU - Gouda, Moustafa A.

AU - Hussein, Belal H.M.

AU - El-Demerdash, Amr

AU - Ibrahim, Mona E.

AU - Salem, Mohammed A.

AU - Helal, Mohamed H.

AU - Hamama, Wafaa S.

PY - 2020

Y1 - 2020

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AB - Coumarins are a set of polyphenolic compounds isolated from plant product tonka bean, cou-marou in 1820. They belong to the family of benzopyrones, which includes benzene ring joined with the aid of a pyrone ring. Coumarins have attracted great attention of medicinal chemists and pharmacologists in recent years as they been confirmed to bear diverse pharmacological activities like anti-inflammatory and analgesic, anti oxidant, anticancer, etc. This review highlights the method of preparation, chemical reactivity, and organic properties such as anti-inflammatory, anticoagulant, antioxidant, anticancer and analgesic activities, of coumarins and their analogues.

KW - Anti-inflammatory and analgesic activity

KW - Anticoagulant activity

KW - Antioxidant and anticancer activity

KW - Chloroacetyl chloride

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A review: Synthesis and medicinal importance of coumarins and their analogues (part ii)

Abstract

Keywords

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