A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome

Susan J van Dijk; Edith J M Feskens; Marieke B Bos; Dianne W M Hoelen; Rik Heijligenberg; Mechteld Grootte Bromhaar; Lisette C P G M de Groot; Jeanne H M de Vries; Michael Müller; Lydia A Afman

doi:10.3945/ajcn.2009.27792

A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome

Susan J van Dijk
, Edith J M Feskens
, Marieke B Bos
, Dianne W M Hoelen
, Rik Heijligenberg
, Mechteld Grootte Bromhaar
, Lisette C P G M de Groot
, Jeanne H M de Vries
, Michael Müller
, Lydia A Afman

Research output: Contribution to journal › Article › peer-review

262 Citations (Scopus)

Abstract

Changes in dietary fat composition could lower the risk of developing metabolic syndrome. Adipose tissue is an interesting tissue in this respect because of its role in lipid metabolism and inflammation.

Original language	English
Pages (from-to)	1656-1664
Number of pages	9
Journal	American Journal of Clinical Nutrition
Volume	90
Issue number	6
DOIs	https://doi.org/10.3945/ajcn.2009.27792
Publication status	Published - Dec 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adiponectin
Adipose Tissue
Adult
Aged
Chemokine CCL5
Complement C3
Fatty Acids
Female
Gene Expression Profiling
Humans
Immunohistochemistry
Insulin Resistance
Lipids
Male
Metabolic Syndrome X
Middle Aged
Oligonucleotide Array Sequence Analysis
PPAR gamma

Access to Document

10.3945/ajcn.2009.27792

Cite this

van Dijk, S. J., Feskens, E. J. M., Bos, M. B., Hoelen, D. W. M., Heijligenberg, R., Bromhaar, M. G., de Groot, L. C. P. G. M., de Vries, J. H. M., Müller, M., & Afman, L. A. (2009). A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. American Journal of Clinical Nutrition, 90(6), 1656-1664. https://doi.org/10.3945/ajcn.2009.27792

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title = "A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome",

abstract = "Changes in dietary fat composition could lower the risk of developing metabolic syndrome. Adipose tissue is an interesting tissue in this respect because of its role in lipid metabolism and inflammation.",

keywords = "Adiponectin, Adipose Tissue, Adult, Aged, Chemokine CCL5, Complement C3, Fatty Acids, Female, Gene Expression Profiling, Humans, Immunohistochemistry, Insulin Resistance, Lipids, Male, Metabolic Syndrome X, Middle Aged, Oligonucleotide Array Sequence Analysis, PPAR gamma",

author = "\{van Dijk\}, \{Susan J\} and Feskens, \{Edith J M\} and Bos, \{Marieke B\} and Hoelen, \{Dianne W M\} and Rik Heijligenberg and Bromhaar, \{Mechteld Grootte\} and \{de Groot\}, \{Lisette C P G M\} and \{de Vries\}, \{Jeanne H M\} and Michael M{\"u}ller and Afman, \{Lydia A\}",

year = "2009",

month = dec,

doi = "10.3945/ajcn.2009.27792",

language = "English",

volume = "90",

pages = "1656--1664",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

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}

van Dijk, SJ, Feskens, EJM, Bos, MB, Hoelen, DWM, Heijligenberg, R, Bromhaar, MG, de Groot, LCPGM, de Vries, JHM, Müller, M & Afman, LA 2009, 'A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome', American Journal of Clinical Nutrition, vol. 90, no. 6, pp. 1656-1664. https://doi.org/10.3945/ajcn.2009.27792

A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. / van Dijk, Susan J; Feskens, Edith J M; Bos, Marieke B et al.
In: American Journal of Clinical Nutrition, Vol. 90, No. 6, 12.2009, p. 1656-1664.

Research output: Contribution to journal › Article › peer-review

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AU - van Dijk, Susan J

AU - Feskens, Edith J M

AU - Bos, Marieke B

AU - Hoelen, Dianne W M

AU - Heijligenberg, Rik

AU - Bromhaar, Mechteld Grootte

AU - de Groot, Lisette C P G M

AU - de Vries, Jeanne H M

AU - Müller, Michael

AU - Afman, Lydia A

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KW - Chemokine CCL5

KW - Complement C3

KW - Fatty Acids

KW - Female

KW - Gene Expression Profiling

KW - Humans

KW - Immunohistochemistry

KW - Insulin Resistance

KW - Lipids

KW - Male

KW - Metabolic Syndrome X

KW - Middle Aged

KW - Oligonucleotide Array Sequence Analysis

KW - PPAR gamma

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DO - 10.3945/ajcn.2009.27792

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