A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid

Philip C. Bulman Page; David C. Leach; Colin M. Hayman; A. Sazali Hamzah; Steven M. Allin; Vickie McKee

doi:10.1055/s-2003-39290

A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid

Philip C. Bulman Page, David C. Leach, Colin M. Hayman, A. Sazali Hamzah, Steven M. Allin, Vickie McKee

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.

Original language	English
Pages (from-to)	1025-1027
Number of pages	3
Journal	Synlett
Volume	2003
Issue number	7
DOIs	https://doi.org/10.1055/s-2003-39290
Publication status	Published - 2003

Keywords

PROTEASOME INHIBITORS
Dieckmann
lactacystin
ROUTE
ANALOGS
clasto-lactacystin
TOOLS
D-GLUCOSE
EFFICIENT
BETA-LACTONE
acylation
(+)-LACTACYSTIN

Access to Document

10.1055/s-2003-39290

Cite this

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title = "A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid",

abstract = "An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.",

keywords = "PROTEASOME INHIBITORS, Dieckmann, lactacystin, ROUTE, ANALOGS, clasto-lactacystin, TOOLS, D-GLUCOSE, EFFICIENT, BETA-LACTONE, acylation, (+)-LACTACYSTIN",

author = "{Bulman Page}, {Philip C.} and Leach, {David C.} and Hayman, {Colin M.} and Hamzah, {A. Sazali} and Allin, {Steven M.} and Vickie McKee",

year = "2003",

doi = "10.1055/s-2003-39290",

language = "English",

volume = "2003",

pages = "1025--1027",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "7",

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T1 - A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid

AU - Bulman Page, Philip C.

AU - Leach, David C.

AU - Hayman, Colin M.

AU - Hamzah, A. Sazali

AU - Allin, Steven M.

AU - McKee, Vickie

PY - 2003

Y1 - 2003

N2 - An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.

AB - An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.

KW - PROTEASOME INHIBITORS

KW - Dieckmann

KW - lactacystin

KW - ROUTE

KW - ANALOGS

KW - clasto-lactacystin

KW - TOOLS

KW - D-GLUCOSE

KW - EFFICIENT

KW - BETA-LACTONE

KW - acylation

KW - (+)-LACTACYSTIN

U2 - 10.1055/s-2003-39290

DO - 10.1055/s-2003-39290

M3 - Article

SN - 0936-5214

VL - 2003

SP - 1025

EP - 1027

JO - Synlett

JF - Synlett

IS - 7

ER -