A simple one-pot method for the synthesis of partially protected mono- and disaccharide building blocks using an orthoesterification-benzylation-orthoester rearrangement approach

Balaram Mukhopadhyay, Robert A. Field

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

A simple one-pot method is reported for making partially protected glycosyl acceptors from O-methyl or S-alkyl/aryl glycosides of D-glucose, D-galactose, D-arabinose, L-rhamnose, L-fucose and lactose via orthoester formation, benzylation and selective hydrolysis.

Original languageEnglish
Pages (from-to)2149-2152
Number of pages4
JournalCarbohydrate Research
Volume338
Issue number20
Early online date12 Aug 2003
DOIs
Publication statusPublished - 26 Sep 2003

Keywords

  • Benzylation
  • One-pot reaction
  • Orthoester
  • Rearrangement

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