A systematic review investigating the efficacy of laterally wedged insoles for medial knee osteoarthritis

P Penny, J Geere, Toby O Smith

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


A conservative management strategy for knee osteoarthritis is the lateral wedge insole (LWI). The theoretical basis for this intervention is to correct tibiofemoral malalignment, thereby reducing pain and optimising function. This systematic review evaluates the evidence on the effectiveness and safety of LWI for the treatment for knee osteoarthritis. A systematic review was performed, searching published (MEDLINE, AMED, EMBASE, CINAHL, Cochrane Library) and unpublished literature from their inception to August 2012. Randomised controlled trials (RCTs) were included that compared the use of LWI with a neutral insole or control intervention for people with medial compartment osteoarthritis. Risk of bias and clinical relevance were assessed, and outcomes were analysed through meta-analysis. From a total of 3,105 citations, 10 studies adhered to the a priori eligibility criteria. These included 1,095 people; 535 participants were allocated to receive LWI insoles compared to 509 in control groups. Eight per cent of papers were of high quality with low risk of bias. There was no statistically significant difference between LWI and neutral insoles for pain, function, analgesic requirement, compliance or complications (p ≥ 0.07). Those who received LWI demonstrated lower non-steroidal anti-inflammatory drug requirements (p
Original languageEnglish
Pages (from-to)2529-2538
Number of pages10
JournalRheumatology International
Issue number10
Early online date24 Apr 2013
Publication statusPublished - 1 Oct 2013


  • Orthosis
  • Insoles
  • Medial compartment
  • Tibiofemoral
  • Degenerative
  • Biomechanics

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