A two-directional synthesis of (±)-perhydrohistrionicotoxin

Robert A. Stockman, Alex Sinclair, Louise G. Arini, Peter Szeto, David L. Hughes

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46 Citations (Scopus)


An entirely two-directional synthesis of (±)-perhydrohistrionicotoxin is presented, utilizing a tandem oxime formation/Michael addition/[3 + 2] cycloaddition as the key step. This approach also constitutes formal syntheses of (±)-histrionicotoxin and (±)-histrionicotoxin 235A.
Original languageEnglish
Pages (from-to)1598-1602
Number of pages5
JournalThe Journal of Organic Chemistry
Issue number5
Early online date6 Feb 2004
Publication statusPublished - 1 Mar 2004

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