TY - JOUR
T1 - A view on vitamin D: A pleiotropic factor?
AU - Giustina, Andrea
AU - Lazaretti-Castro, Marise
AU - Martineau, Adrian R.
AU - Mason, Rebecca S.
AU - Rosen, Clifford J.
AU - Schoenmakers, Inez
N1 - Funding Information:
A.G. is a consultant for Abiogen, Ipsen, Pfizer, Recordati and Takeda, and is a recipient of research grants (to his institution) from Pfizer and Takeda. A.R.M. declares receipt of funding in the last 36 months to support vitamin D research from the following companies which manufacture or sell vitamin D supplements: Pharma Nord Ltd, DSM Nutritional Products Ltd, Thornton & Ross Ltd and Hyphens Pharma Ltd. A.R.M. also declares receipt of vitamin D capsules for clinical trial use from Pharma Nord Ltd, Synergy Biologics Ltd and Cytoplan Ltd; support for attending meetings from Pharma Nord Ltd and Abiogen Pharma Ltd; receipt of consultancy fees from DSM Nutritional Products Ltd and Qiagen Ltd; and receipt of a speaker fee from the Linus Pauling Institute. A.R.M. declares participation on Data and Safety Monitoring Boards for the VITALITY trial (Vitamin D for Adolescents with HIV to Reduce Musculoskeletal Morbidity and Immunopathology, Pan African Clinical Trials Registry ref PACTR20200989766029) and the Trial of Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India (ClinicalTrials.gov ref NCT04641195); and unpaid work as a Programme Committee member for the Vitamin D Workshop. R.S.M. has received speaker fees from Sanofi Australia. M.L.-C., C.J.R. and I.S. declare no competing interests.
PY - 2024/4
Y1 - 2024/4
N2 - Vitamin D is precursor of the steroid hormone calcitriol and has important functions throughout the body, including increasing intestinal absorption of calcium, magnesium and phosphate. Vitamin D deficiency has been linked with a range of disorders, including several bone diseases. However, large trials of vitamin D supplementation have produced mixed results. Here, experts from around the world discuss several key questions in the vitamin D research and clinical fields.
AB - Vitamin D is precursor of the steroid hormone calcitriol and has important functions throughout the body, including increasing intestinal absorption of calcium, magnesium and phosphate. Vitamin D deficiency has been linked with a range of disorders, including several bone diseases. However, large trials of vitamin D supplementation have produced mixed results. Here, experts from around the world discuss several key questions in the vitamin D research and clinical fields.
UR - http://www.scopus.com/inward/record.url?scp=85182860913&partnerID=8YFLogxK
U2 - 10.1038/s41574-023-00942-0
DO - 10.1038/s41574-023-00942-0
M3 - Article
AN - SCOPUS:85182860913
VL - 20
SP - 202
EP - 208
JO - Nature Reviews Endocrinology
JF - Nature Reviews Endocrinology
SN - 1759-5029
IS - 4
ER -
