A weekly alternating diet between caloric restriction and medium fat protects the liver from fatty liver development in middle-aged C57BL/6J mice

Fenni Rusli, Mark V Boekschoten, Arantza Aguirre Zubia, Carolien Lute, Michael Müller, Wilma T Steegenga

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


We investigated whether a novel dietary intervention consisting of an every-other-week calorie-restricted diet could prevent nonalcoholic fatty liver disease (NAFLD) development induced by a medium-fat (MF) diet.
Original languageEnglish
Pages (from-to)533–543
Number of pages11
JournalMolecular Nutrition & Food Research
Issue number3
Early online date15 Dec 2014
Publication statusPublished - Mar 2015


  • Dietary intervention
  • Gene expression profile
  • Metabolic markers
  • Nonalcoholic fatty liver disease
  • Steatosis

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