Abnormalities of vascular structure and function in children with Perthes disease

Daniel C. Perry; Daniel J. Green; Colin E. Bruce; Daniel Pope; Peter Dangerfield; Mary Jane Platt; Andrew J. Hall; Helen Jones

doi:10.1542/peds.2011-3269

Abnormalities of vascular structure and function in children with Perthes disease

Daniel C. Perry, Daniel J. Green, Colin E. Bruce, Daniel Pope, Peter Dangerfield, Mary Jane Platt, Andrew J. Hall, Helen Jones

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Perthes disease is a childhood precipitant to osteoarthritis of the hip, for which the etiology and mechanism are unknown. There is mounting evidence to suggest a vascular insult is responsible for disease, and it is suggested that this may have long-term implications for the vascular health of affected individuals. This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease.

Original language	English
Pages (from-to)	e126-31
Journal	Pediatrics
Volume	130
Issue number	1
DOIs	https://doi.org/10.1542/peds.2011-3269
Publication status	Published - Jul 2012

Keywords

Adolescent
Blood Flow Velocity
Body Height
Brachial Artery
Case-Control Studies
Child
Child, Preschool
Female
Humans
Legg-Calve-Perthes Disease
Logistic Models
Male
Multivariate Analysis
Ultrasonography, Doppler

Access to Document

10.1542/peds.2011-3269

Cite this

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title = "Abnormalities of vascular structure and function in children with Perthes disease",

abstract = "Perthes disease is a childhood precipitant to osteoarthritis of the hip, for which the etiology and mechanism are unknown. There is mounting evidence to suggest a vascular insult is responsible for disease, and it is suggested that this may have long-term implications for the vascular health of affected individuals. This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease.",

keywords = "Adolescent, Blood Flow Velocity, Body Height, Brachial Artery, Case-Control Studies, Child, Child, Preschool, Female, Humans, Legg-Calve-Perthes Disease, Logistic Models, Male, Multivariate Analysis, Ultrasonography, Doppler",

author = "Perry, {Daniel C.} and Green, {Daniel J.} and Bruce, {Colin E.} and Daniel Pope and Peter Dangerfield and Platt, {Mary Jane} and Hall, {Andrew J.} and Helen Jones",

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AU - Perry, Daniel C.

AU - Green, Daniel J.

AU - Bruce, Colin E.

AU - Pope, Daniel

AU - Dangerfield, Peter

AU - Platt, Mary Jane

AU - Hall, Andrew J.

AU - Jones, Helen

PY - 2012/7

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N2 - Perthes disease is a childhood precipitant to osteoarthritis of the hip, for which the etiology and mechanism are unknown. There is mounting evidence to suggest a vascular insult is responsible for disease, and it is suggested that this may have long-term implications for the vascular health of affected individuals. This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease.

AB - Perthes disease is a childhood precipitant to osteoarthritis of the hip, for which the etiology and mechanism are unknown. There is mounting evidence to suggest a vascular insult is responsible for disease, and it is suggested that this may have long-term implications for the vascular health of affected individuals. This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease.

KW - Adolescent

KW - Blood Flow Velocity

KW - Body Height

KW - Brachial Artery

KW - Case-Control Studies

KW - Child

KW - Child, Preschool

KW - Female

KW - Humans

KW - Legg-Calve-Perthes Disease

KW - Logistic Models

KW - Male

KW - Multivariate Analysis

KW - Ultrasonography, Doppler

U2 - 10.1542/peds.2011-3269

DO - 10.1542/peds.2011-3269

M3 - Article

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VL - 130

SP - e126-31

JO - Pediatrics

JF - Pediatrics

SN - 0031-4005

IS - 1

ER -