Abnormalities of vascular structure and function in children with Perthes disease

Daniel C. Perry, Daniel J. Green, Colin E. Bruce, Daniel Pope, Peter Dangerfield, Mary Jane Platt, Andrew J. Hall, Helen Jones

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21 Citations (Scopus)

Abstract

Perthes disease is a childhood precipitant to osteoarthritis of the hip, for which the etiology and mechanism are unknown. There is mounting evidence to suggest a vascular insult is responsible for disease, and it is suggested that this may have long-term implications for the vascular health of affected individuals. This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease.
Original languageEnglish
Pages (from-to)e126-31
JournalPediatrics
Volume130
Issue number1
DOIs
Publication statusPublished - Jul 2012

Keywords

  • Adolescent
  • Blood Flow Velocity
  • Body Height
  • Brachial Artery
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Legg-Calve-Perthes Disease
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Ultrasonography, Doppler

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