Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects

G. Mazza, Colin D. Kay, Tony Cottrell, Bruce J. Holub

Research output: Contribution to journalArticlepeer-review

409 Citations (Scopus)


In recent years, numerous studies have shown that the polyphenolics present in fruit and vegetable products exhibit a wide range of biological effects. However, there is little reliable information on the absorption of glycosylated and acylated anthocyanins in humans. In the present study, the absorption of anthocyanins in humans was investigated after the consumption of a high-fat meal with a freeze-dried blueberry powder containing 25 individual anthocyanins including 6 acylated structures. Nineteen of the 25 anthocyanins present in the blueberries were detected in human blood serum. Furthermore, the appearance of total anthocyanins in the serum was directly correlated with an increase in serum antioxidant capacity (ORAC(acetone), P
Original languageEnglish
Pages (from-to)7731-7737
Number of pages7
JournalJournal of Agricultural and Food Chemistry
Issue number26
Publication statusPublished - 18 Dec 2002


  • Absorption
  • Acylation
  • Anthocyanins
  • Antioxidants
  • Blueberry Plant
  • Chromatography, High Pressure Liquid
  • Dietary Fats
  • Fruit
  • Glucosides
  • Glycosylation
  • Humans
  • Kinetics
  • Male
  • Middle Aged

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