Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase

Robert A. Field, David C. A. Neville, Roland W. Smith, Michael A. J. Ferguson

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12 Citations (Scopus)

Abstract

A series of 4- and 6-substituted derivatives of benzyl N-acetyl-β-D-glucosaminide were prepared and assessed as inhibitors of bovine β-1,4-galactosyl transferase. Of the azido, amino, and acetamido compounds tested, only the 4-amino compound (2) produced significant inhibition of this enzyme.

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume4
Issue number3
DOIs
Publication statusPublished - 10 Feb 1994

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