TY - UNPB
T1 - AePUb promoter length modulates gene expression in Aedes aegypti
AU - Anderson, Michelle A. E.
AU - Leftwich, Philip T.
AU - Wilson, Ray
AU - Paladino, Leonela Z. Carabajal
AU - Basu, Sanjay
AU - Rooney, Sara
AU - Adelman, Zach N.
AU - Alphey, Luke
PY - 2023/8/11
Y1 - 2023/8/11
N2 - Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.
AB - Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.
U2 - 10.1101/2023.08.11.553001
DO - 10.1101/2023.08.11.553001
M3 - Preprint
BT - AePUb promoter length modulates gene expression in Aedes aegypti
PB - biorxiv
ER -