Age-associated changes in mesenteric arteries

M Balsitis; E MacDonald; A McDonald; I Davidson; J D Fulton; P J Scott; R Wadsworth; M Wilkinson

doi:10.1093/ageing/21.5.328

Age-associated changes in mesenteric arteries

M Balsitis, E MacDonald, A McDonald, I Davidson, J D Fulton, P J Scott, R Wadsworth, M Wilkinson

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Vascular disease increases in incidence with age and is the commonest cause of morbidity and mortality among elderly people. Hypertension is associated with hypertrophy of the arterial media. This study was designed to investigate changes in arterial structure that may occur with age independent of blood pressure. Collapsed sections of human mesenteric arteries (external diameter 2-3 mm) were measured using a semi-automatic image analysis system. There was a nonlinear increase in both the wall/lumen area ratio and the relative intimal area with age. There were no significant relationships between blood pressure and either the wall/lumen ratio or the relative intimal area.

Original language	English
Pages (from-to)	328-332
Number of pages	5
Journal	Age and Ageing
Volume	21
Issue number	5
DOIs	https://doi.org/10.1093/ageing/21.5.328
Publication status	Published - Sep 1992

Keywords

Adult
Aged
Aged, 80 and over
Blood Pressure
Female
Fibromuscular Dysplasia
Humans
Hypertension
Image Processing, Computer-Assisted
Inflammatory Bowel Diseases
Intestinal Neoplasms
Male
Mesenteric Arteries
Mesenteric Vascular Occlusion
Microcomputers
Microscopy
Middle Aged
Muscle, Smooth, Vascular

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/ageing/21.5.328

Cite this

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title = "Age-associated changes in mesenteric arteries",

abstract = "Vascular disease increases in incidence with age and is the commonest cause of morbidity and mortality among elderly people. Hypertension is associated with hypertrophy of the arterial media. This study was designed to investigate changes in arterial structure that may occur with age independent of blood pressure. Collapsed sections of human mesenteric arteries (external diameter 2-3 mm) were measured using a semi-automatic image analysis system. There was a nonlinear increase in both the wall/lumen area ratio and the relative intimal area with age. There were no significant relationships between blood pressure and either the wall/lumen ratio or the relative intimal area.",

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author = "M Balsitis and E MacDonald and A McDonald and I Davidson and Fulton, {J D} and Scott, {P J} and R Wadsworth and M Wilkinson",

year = "1992",

month = sep,

doi = "10.1093/ageing/21.5.328",

language = "English",

volume = "21",

pages = "328--332",

journal = "Age and Ageing",

issn = "0002-0729",

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T1 - Age-associated changes in mesenteric arteries

AU - Balsitis, M

AU - MacDonald, E

AU - McDonald, A

AU - Davidson, I

AU - Fulton, J D

AU - Scott, P J

AU - Wadsworth, R

AU - Wilkinson, M

PY - 1992/9

Y1 - 1992/9

N2 - Vascular disease increases in incidence with age and is the commonest cause of morbidity and mortality among elderly people. Hypertension is associated with hypertrophy of the arterial media. This study was designed to investigate changes in arterial structure that may occur with age independent of blood pressure. Collapsed sections of human mesenteric arteries (external diameter 2-3 mm) were measured using a semi-automatic image analysis system. There was a nonlinear increase in both the wall/lumen area ratio and the relative intimal area with age. There were no significant relationships between blood pressure and either the wall/lumen ratio or the relative intimal area.

AB - Vascular disease increases in incidence with age and is the commonest cause of morbidity and mortality among elderly people. Hypertension is associated with hypertrophy of the arterial media. This study was designed to investigate changes in arterial structure that may occur with age independent of blood pressure. Collapsed sections of human mesenteric arteries (external diameter 2-3 mm) were measured using a semi-automatic image analysis system. There was a nonlinear increase in both the wall/lumen area ratio and the relative intimal area with age. There were no significant relationships between blood pressure and either the wall/lumen ratio or the relative intimal area.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Blood Pressure

KW - Female

KW - Fibromuscular Dysplasia

KW - Humans

KW - Hypertension

KW - Image Processing, Computer-Assisted

KW - Inflammatory Bowel Diseases

KW - Intestinal Neoplasms

KW - Male

KW - Mesenteric Arteries

KW - Mesenteric Vascular Occlusion

KW - Microcomputers

KW - Microscopy

KW - Middle Aged

KW - Muscle, Smooth, Vascular

U2 - 10.1093/ageing/21.5.328

DO - 10.1093/ageing/21.5.328

M3 - Article

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VL - 21

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EP - 332

JO - Age and Ageing

JF - Age and Ageing

SN - 0002-0729

IS - 5

ER -