Age, neuropathology, and dementia

George M Savva; Stephen B Wharton; Paul G Ince; Gillian Forster; Fiona E Matthews; Carol Brayne; Medical Research Council Cognitive Function and Ageing Study

doi:10.1056/NEJMoa0806142

Age, neuropathology, and dementia

George M Savva, Stephen B Wharton, Paul G Ince, Gillian Forster, Fiona E Matthews, Carol Brayne, Medical Research Council Cognitive Function and Ageing Study

Norwich Epidemiology Centre

Research output: Contribution to journal › Article › peer-review

739 Citations (SciVal)

Abstract

Research in Alzheimer's disease is focused mainly on younger old persons, whereas studies involving very old persons report attenuated relationships between the pathological features of Alzheimer's disease and dementia.

Original language	English
Pages (from-to)	2302-2309
Number of pages	8
Journal	New England Journal of Medicine
Volume	360
Issue number	22
DOIs	https://doi.org/10.1056/NEJMoa0806142
Publication status	Published - 28 May 2009

Keywords

Age Factors
Aged
Aged, 80 and over
Aging
Alzheimer Disease
Atrophy
Autopsy
Brain
Cerebrovascular Disorders
Dementia
Female
Humans
Lewy Bodies
Male
Odds Ratio
Plaque, Amyloid

Access to Document

10.1056/NEJMoa0806142

Cite this

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title = "Age, neuropathology, and dementia",

abstract = "Research in Alzheimer's disease is focused mainly on younger old persons, whereas studies involving very old persons report attenuated relationships between the pathological features of Alzheimer's disease and dementia.",

keywords = "Age Factors, Aged, Aged, 80 and over, Aging, Alzheimer Disease, Atrophy, Autopsy, Brain, Cerebrovascular Disorders, Dementia, Female, Humans, Lewy Bodies, Male, Odds Ratio, Plaque, Amyloid",

author = "Savva, {George M} and Wharton, {Stephen B} and Ince, {Paul G} and Gillian Forster and Matthews, {Fiona E} and Carol Brayne and {Medical Research Council Cognitive Function and Ageing Study}",

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AU - Wharton, Stephen B

AU - Ince, Paul G

AU - Forster, Gillian

AU - Matthews, Fiona E

AU - Brayne, Carol

AU - Medical Research Council Cognitive Function and Ageing Study

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KW - Aged, 80 and over

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KW - Alzheimer Disease

KW - Atrophy

KW - Autopsy

KW - Brain

KW - Cerebrovascular Disorders

KW - Dementia

KW - Female

KW - Humans

KW - Lewy Bodies

KW - Male

KW - Odds Ratio

KW - Plaque, Amyloid

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