Age, neuropathology, and dementia

George M Savva, Stephen B Wharton, Paul G Ince, Gillian Forster, Fiona E Matthews, Carol Brayne, Medical Research Council Cognitive Function and Ageing Study

Research output: Contribution to journalArticlepeer-review

722 Citations (Scopus)


Research in Alzheimer's disease is focused mainly on younger old persons, whereas studies involving very old persons report attenuated relationships between the pathological features of Alzheimer's disease and dementia.
Original languageEnglish
Pages (from-to)2302-2309
Number of pages8
JournalNew England Journal of Medicine
Issue number22
Publication statusPublished - 28 May 2009


  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging
  • Alzheimer Disease
  • Atrophy
  • Autopsy
  • Brain
  • Cerebrovascular Disorders
  • Dementia
  • Female
  • Humans
  • Lewy Bodies
  • Male
  • Odds Ratio
  • Plaque, Amyloid

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