TY - JOUR
T1 - An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: Emerging 'novel psychoactive drugs'
AU - Arunotayanun, Warunya
AU - Dalley, Jeffrey W.
AU - Huang, Xi-Ping
AU - Setola, Vincent
AU - Treble, Ric
AU - Iversen, Leslie
AU - Roth, Bryan L.
AU - Gibbons, Simon
PY - 2013/6/1
Y1 - 2013/6/1
N2 - Novel Psychoactive Drugs (NPD) can be sold without restriction and are often synthetic analogues of controlled drugs. The tryptamines are an important class of NPD as they bind to the various serotonin (5-HT) receptor subtypes and cause psychosis and hallucinations that can lead to injury or death through misadventure. Here we report on the structure elucidation and receptor binding profiles of two widely marketed tryptamine-derived NPDs, namely alpha-methyl-tryptamine and 5-methoxy-N,N-diallyl-tryptamine.
AB - Novel Psychoactive Drugs (NPD) can be sold without restriction and are often synthetic analogues of controlled drugs. The tryptamines are an important class of NPD as they bind to the various serotonin (5-HT) receptor subtypes and cause psychosis and hallucinations that can lead to injury or death through misadventure. Here we report on the structure elucidation and receptor binding profiles of two widely marketed tryptamine-derived NPDs, namely alpha-methyl-tryptamine and 5-methoxy-N,N-diallyl-tryptamine.
U2 - 10.1016/j.bmcl.2013.03.066
DO - 10.1016/j.bmcl.2013.03.066
M3 - Article
SN - 0960-894X
VL - 23
SP - 3411
EP - 3415
JO - Bioorganic & Medicinal Chemistry Letters
JF - Bioorganic & Medicinal Chemistry Letters
IS - 11
ER -