Antibacterial constituents of Neohyptis paniculata

M. Mukhlesur Rahman, Simon Gibbons

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


A new α-pyrone, 6R-[5R,6S-diacetyloxy-1Z,3E-heptadienyl]-5,6-dihydro-2H-pyran-2one (1), along with six known compounds including an α-pyrone, flavones and terpenes was isolated from the aerial parts of Neohyptis paniculata. The structure of 1 was established unambiguously by MS and a series of 1D and 2D-NMR spectroscopic analyses. The antibacterial activity of the compounds (1-7) was investigated against five strains of multi-drug resistant (MDR) and methicillin-resistant Staphylococcus aureus and minimum inhibitory concentrations (MICs) of these compounds were found to be in the range of 64-256 μg/mL.
Original languageEnglish
Pages (from-to)269-272
Number of pages4
Early online date21 Jul 2015
Publication statusPublished - Sep 2015

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