Antibacterial Galloylated Alkylphloroglucinol Glucosides from Myrtle (Myrtus communis)

Giovanni Appendino; Lucia Maxia; Piergiorgio Bettoni; Monica Locatelli; Carola Valdivia; Mauro Ballero; Michael Stavri; Simon Gibbons; Olov Sterner

doi:10.1021/np050462w

Antibacterial Galloylated Alkylphloroglucinol Glucosides from Myrtle (Myrtus communis)

Giovanni Appendino, Lucia Maxia, Piergiorgio Bettoni, Monica Locatelli, Carola Valdivia, Mauro Ballero, Michael Stavri, Simon Gibbons, Olov Sterner

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

An investigation of the polar glycosidic fraction from the leaves of myrtle afforded four galloylated nonprenylated phloroglucinol glucosides (3a−d) related to the endoperoxide hormone G3 (4) in terms of structure and biogenesis. Despite their close similarity, significant antibacterial activity was shown only by one of these compounds (3b, gallomyrtucommulone B), while the G3 hormone (4) was inactive.

Original language	English
Pages (from-to)	251-254
Number of pages	5
Journal	Journal of Natural Products
Volume	69
Issue number	2
DOIs	https://doi.org/10.1021/np050462w
Publication status	Published - 1 Feb 2006

Access to Document

10.1021/np050462w

https://pubs.acs.org/doi/10.1021/np050462w

Cite this

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title = "Antibacterial Galloylated Alkylphloroglucinol Glucosides from Myrtle (Myrtus communis)",

abstract = "An investigation of the polar glycosidic fraction from the leaves of myrtle afforded four galloylated nonprenylated phloroglucinol glucosides (3a−d) related to the endoperoxide hormone G3 (4) in terms of structure and biogenesis. Despite their close similarity, significant antibacterial activity was shown only by one of these compounds (3b, gallomyrtucommulone B), while the G3 hormone (4) was inactive. ",

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Antibacterial Galloylated Alkylphloroglucinol Glucosides from Myrtle (Myrtus communis). / Appendino, Giovanni; Maxia, Lucia; Bettoni, Piergiorgio; Locatelli, Monica; Valdivia, Carola; Ballero, Mauro; Stavri, Michael; Gibbons, Simon; Sterner, Olov.

In: Journal of Natural Products, Vol. 69, No. 2, 01.02.2006, p. 251-254.

Research output: Contribution to journal › Article › peer-review

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AU - Appendino, Giovanni

AU - Maxia, Lucia

AU - Bettoni, Piergiorgio

AU - Locatelli, Monica

AU - Valdivia, Carola

AU - Ballero, Mauro

AU - Stavri, Michael

AU - Gibbons, Simon

AU - Sterner, Olov

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AB - An investigation of the polar glycosidic fraction from the leaves of myrtle afforded four galloylated nonprenylated phloroglucinol glucosides (3a−d) related to the endoperoxide hormone G3 (4) in terms of structure and biogenesis. Despite their close similarity, significant antibacterial activity was shown only by one of these compounds (3b, gallomyrtucommulone B), while the G3 hormone (4) was inactive.

U2 - 10.1021/np050462w

DO - 10.1021/np050462w

M3 - Article

VL - 69

SP - 251

EP - 254

JO - Journal of Natural Products

JF - Journal of Natural Products

SN - 0163-3864

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