Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study

Chris Fox; Kathryn Richardson; Ian D. Maidment; George M. Savva; Fiona E. Matthews; David Smithard; Simon Coulton; Cornelius Katona; Malaz A. Boustani; Carol Brayne

doi:10.1111/j.1532-5415.2011.03491.x

Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study

Chris Fox, Kathryn Richardson, Ian D. Maidment, George M. Savva, Fiona E. Matthews, David Smithard, Simon Coulton, Cornelius Katona, Malaz A. Boustani, Carol Brayne

Research output: Contribution to journal › Article › peer-review

482 Citations (Scopus)

Abstract

To determine whether the use of medications with possible and definite anticholinergic activity increases the risk of cognitive impairment and mortality in older people and whether risk is cumulative.

Original language	English
Pages (from-to)	1477-1483
Number of pages	7
Journal	Journal of the American Geriatrics Society
Volume	59
Issue number	8
DOIs	https://doi.org/10.1111/j.1532-5415.2011.03491.x
Publication status	Published - Aug 2011

Keywords

Aged
Aged, 80 and over
Cholinergic Antagonists
Cognition Disorders
Comorbidity
England
Female
Geriatric Assessment
Health Surveys
Humans
Longitudinal Studies
Male
Mental Status Schedule
Odds Ratio
Prospective Studies
Psychometrics
Risk Factors
Wales

Access to Document

10.1111/j.1532-5415.2011.03491.x

Cite this

Fox, C., Richardson, K., Maidment, I. D., Savva, G. M., Matthews, F. E., Smithard, D., Coulton, S., Katona, C., Boustani, M. A., & Brayne, C. (2011). Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study. Journal of the American Geriatrics Society, 59(8), 1477-1483. https://doi.org/10.1111/j.1532-5415.2011.03491.x

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title = "Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study",

abstract = "To determine whether the use of medications with possible and definite anticholinergic activity increases the risk of cognitive impairment and mortality in older people and whether risk is cumulative.",

keywords = "Aged, Aged, 80 and over, Cholinergic Antagonists, Cognition Disorders, Comorbidity, England, Female, Geriatric Assessment, Health Surveys, Humans, Longitudinal Studies, Male, Mental Status Schedule, Odds Ratio, Prospective Studies, Psychometrics, Risk Factors, Wales",

author = "Chris Fox and Kathryn Richardson and Maidment, {Ian D.} and Savva, {George M.} and Matthews, {Fiona E.} and David Smithard and Simon Coulton and Cornelius Katona and Boustani, {Malaz A.} and Carol Brayne",

note = "{\textcopyright} 2011, Copyright the Authors. Journal compilation {\textcopyright} 2011, The American Geriatrics Society.",

year = "2011",

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doi = "10.1111/j.1532-5415.2011.03491.x",

language = "English",

volume = "59",

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Fox, C, Richardson, K, Maidment, ID, Savva, GM, Matthews, FE, Smithard, D, Coulton, S, Katona, C, Boustani, MA & Brayne, C 2011, 'Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study', Journal of the American Geriatrics Society, vol. 59, no. 8, pp. 1477-1483. https://doi.org/10.1111/j.1532-5415.2011.03491.x

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AU - Maidment, Ian D.

AU - Savva, George M.

AU - Matthews, Fiona E.

AU - Smithard, David

AU - Coulton, Simon

AU - Katona, Cornelius

AU - Boustani, Malaz A.

AU - Brayne, Carol

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KW - Cognition Disorders

KW - Comorbidity

KW - England

KW - Female

KW - Geriatric Assessment

KW - Health Surveys

KW - Humans

KW - Longitudinal Studies

KW - Male

KW - Mental Status Schedule

KW - Odds Ratio

KW - Prospective Studies

KW - Psychometrics

KW - Risk Factors

KW - Wales

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DO - 10.1111/j.1532-5415.2011.03491.x

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