Apple polyphenols in human and animal health*

Andy Wai Kan Yeung, Nikolay T. Tzvetkov, Amr El-Demerdash, Olaf K. Horbanczuk, Niranjan Das, Vasil Pirgozliev, Massimo Lucarini, Alessandra Durazzo, Eliana B. Souto, Antonello Santini, Hari Prasad Devkota, Md Sahab Uddin, Javier Echeverría, Dongdong Wang, Ren You Gan, Mladen Brnčić, Reni E. Kalfin, Lyubka P. Tancheva, Devesh Tewari, Ioana Berindan-NeagoeSilvestre Sampino, Nina Strzałkowska, Joanna Marchewka, Artur Jóźwik, Jarosław Olav Horbańczuk, Atanas G. Atanasov

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)

    Abstract

    Apples contain substantial amounts of polyphenols, and diverse phenolics – mainly flavonoids and phenolic acids, have been identified in their flesh and skins. This work aimed to analyze the overall landscape of the research literature published to date on apple phenolic compounds in the context of human and animal health. The Web of Science Core Collection electronic database was queried with (apple* polyphenol*) AND (health* OR illness* OR disease* OR medic* OR pharma*) to identify relevant papers covering these words and their derivatives in the titles, abstracts, and keywords. The resulted 890 papers were bibliometrically analyzed. The VOSviewer software was utilized to produce term maps that illustrate how the frequent phrases fared in terms of publication and citation data. The apple polyphenol papers received global contributions, particularly from China, Italy, the United States, Spain, and Germany. Examples of frequently mentioned chemicals/chemical classes are quercetin, anthocyanin, catechin, epicatechin, and flavonol, while examples of frequently mentioned medical conditions are cardiovascular disease, atherosclerosis, diabetes, Alzheimer’s disease, and obesity. The potential health benefits of apple polyphenols on humans and animals are diverse and warrant further study.

    Original languageEnglish
    Pages (from-to)105-118
    Number of pages14
    JournalAnimal Science Papers and Reports
    Volume39
    Issue number2
    Publication statusPublished - 2021

    Keywords

    • Alzheimer’s disease
    • Anthocyanin
    • Apple polyphenol
    • Atherosclerosis
    • Cardiovascular disease
    • Diabetes
    • Obesity
    • Quercetin
    • VOSviewer
    • Web of Science

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