Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review

Alison J Davis, Toby O Smith, Caroline B Hing, Nidhi Sofat

Research output: Contribution to journalArticlepeer-review

66 Citations (Scopus)
7 Downloads (Pure)


Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint replacement for larger joints are the standard of care. In light of several recent studies reporting the use of bisphosphonates for OA treatment, our work aimed to evaluate published literature to assess the effectiveness of bisphosphonates in OA treatment.
Original languageEnglish
Article numbere72714
JournalPLoS One
Issue number9
Publication statusPublished - 4 Sep 2013

Cite this