Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study

Clive M Onnie; Sheila A Fisher; Reenal Pattni; Jeremy Sanderson; Alastair Forbes; Cathryn M Lewis; Christopher G Mathew

doi:10.1097/01.MIB.0000209791.98866.ba

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study

Clive M Onnie
, Sheila A Fisher
, Reenal Pattni
, Jeremy Sanderson
, Alastair Forbes
, Cathryn M Lewis
, Christopher G Mathew

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

Allelic variants of the ATP-binding cassette, subfamily B member 1 (ABCB1), also known as the multidrug resistance gene (MDR1) that encodes the membrane-bound efflux transporter P-glycoprotein 170 (PGP-170), have been associated with inflammatory bowel disease but with conflicting results.

Original language	English
Pages (from-to)	263-71
Number of pages	9
Journal	Inflammatory Bowel Diseases
Volume	12
Issue number	4
DOIs	https://doi.org/10.1097/01.MIB.0000209791.98866.ba
Publication status	Published - Apr 2006

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Child
Child, Preschool
DNA
Disease Progression
Female
Follow-Up Studies
Gene Frequency
Genotype
Humans
Inflammatory Bowel Diseases
Male
Middle Aged
Organic Anion Transporters
P-Glycoprotein
Polymorphism, Genetic
Retrospective Studies

Access to Document

10.1097/01.MIB.0000209791.98866.ba

Cite this

Onnie, C. M., Fisher, S. A., Pattni, R., Sanderson, J., Forbes, A., Lewis, C. M., & Mathew, C. G. (2006). Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study. Inflammatory Bowel Diseases, 12(4), 263-71. https://doi.org/10.1097/01.MIB.0000209791.98866.ba

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title = "Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study",

abstract = "Allelic variants of the ATP-binding cassette, subfamily B member 1 (ABCB1), also known as the multidrug resistance gene (MDR1) that encodes the membrane-bound efflux transporter P-glycoprotein 170 (PGP-170), have been associated with inflammatory bowel disease but with conflicting results.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Alleles, Child, Child, Preschool, DNA, Disease Progression, Female, Follow-Up Studies, Gene Frequency, Genotype, Humans, Inflammatory Bowel Diseases, Male, Middle Aged, Organic Anion Transporters, P-Glycoprotein, Polymorphism, Genetic, Retrospective Studies",

author = "Onnie, \{Clive M\} and Fisher, \{Sheila A\} and Reenal Pattni and Jeremy Sanderson and Alastair Forbes and Lewis, \{Cathryn M\} and Mathew, \{Christopher G\}",

year = "2006",

month = apr,

doi = "10.1097/01.MIB.0000209791.98866.ba",

language = "English",

volume = "12",

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issn = "1078-0998",

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Onnie, CM, Fisher, SA, Pattni, R, Sanderson, J, Forbes, A, Lewis, CM & Mathew, CG 2006, 'Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study', Inflammatory Bowel Diseases, vol. 12, no. 4, pp. 263-71. https://doi.org/10.1097/01.MIB.0000209791.98866.ba

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study. / Onnie, Clive M; Fisher, Sheila A; Pattni, Reenal et al.
In: Inflammatory Bowel Diseases, Vol. 12, No. 4, 04.2006, p. 263-71.

Research output: Contribution to journal › Article › peer-review

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KW - Middle Aged

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