Asymmetric aziridination of chalcone promoted by binaphthalene-based chiral amines

Philip Bulman Page, Celine Bordogna, Ian Strutt, Yohan Chan, Benjamin R. Buckley

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Aminimines derived in situ from a number of enantiomerically pure binaphthalene-based tertiary amines have been used for the asymmetric aziridination of chalcone, providing N-unprotected aziridines with ee values of up to 43%. A chiral hydrazinium salt has been isolated for the first time and shown to provide similar yield and enantioselectivity to the in situ process in reaction with chalcone.
Original languageEnglish
Pages (from-to)2067-2072
Number of pages6
Issue number16
Publication statusPublished - 1 Oct 2013


  • chalcone
  • aziridination
  • binaphthalene-based tertiary amines

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